Dosimetry for 177Lu-DKFZ-PSMA-617: a new radiopharmaceutical for the treatment of metastatic prostate cancer

…, A Brunegraf, A Gosewisch, FJ Gildehaus… - European journal of …, 2016 - Springer
Purpose Dosimetry is critical to achieve the optimal therapeutic effect of radioligand therapy
(RLT) with limited side effects. Our aim was to perform image-based absorbed dose …

68Ga-PSMA positron emission tomography/computed tomography provides accurate staging of lymph node regions prior to lymph node dissection in patients with …

…, KM Thierfelder, P Bartenstein, C Faber, FJ Gildehaus… - European urology, 2016 - Elsevier
We evaluated the accuracy of 68 Ga-prostate-specific membrane antigen-HBED-CC ( 68 Ga-PSMA)
positron emission tomography/computed tomography (PET/CT) for nodal staging …

Value of O-(2-[18F]fluoroethyl)-l-tyrosine PET for the diagnosis of recurrent glioma

G Pöpperl, C Götz, W Rachinger, FJ Gildehaus… - European journal of …, 2004 - Springer
Purpose The prognosis of patients with recurrent gliomas depends on reliable and early
diagnosis of tumour recurrence after initial therapy. In this context, magnetic resonance imaging …

Microglial activation states drive glucose uptake and FDG-PET alterations in neurodegenerative diseases

…, C Palleis, BS Rauchmann, FJ Gildehaus… - Science translational …, 2021 - science.org
2-Deoxy-2-[ 18 F]fluoro-d-glucose positron emission tomography (FDG-PET) is widely used
to study cerebral glucose metabolism. Here, we investigated whether the FDG-PET signal is …

Positron emission tomography with O-(2-[18F] fluoroethyl)-l-tyrosine versus magnetic resonance imaging in the diagnosis of recurrent gliomas

W Rachinger, C Goetz, G Pöpperl, FJ Gildehaus… - …, 2005 - journals.lww.com
OBJECTIVE: New treatment modalities are available for patients with glioma, which may
lead to unspecific changes in posttherapeutic magnetic resonance imaging (MRI) findings. …

Value of 11C-choline PET and PET/CT in patients with suspected prostate cancer

…, HC Becker, M Souvatzogluou, FJ Gildehaus… - European journal of …, 2007 - Springer
Purpose: The value and limitations of 11 C-choline PET and PET/CT for the detection of
prostate cancer remain controversial. The aim of this study was to investigate the diagnostic …

Thymosin β4 is an essential paracrine factor of embryonic endothelial progenitor cell–mediated cardioprotection

…, S Müller, M Willhauck, C Spitzweg, FJ Gildehaus… - Circulation, 2008 - ahajournals.org
Background— Prolonged myocardial ischemia results in cardiomyocyte loss despite successful
revascularization. We have reported that retrograde application of embryonic endothelial …

Glial activation and glucose metabolism in a transgenic amyloid mouse model: a triple-tracer PET study

…, R Beck, S Lindner, FJ Gildehaus… - Journal of Nuclear …, 2016 - jnm.snmjournals.org
Amyloid imaging by small-animal PET in models of Alzheimer disease (AD) offers the possibility
to track amyloidogenesis and brain energy metabolism. Because microglial activation is …

First clinical results for PSMA-targeted α-therapy using 225Ac-PSMA-I&T in advanced-mCRPC patients

MJ Zacherl, FJ Gildehaus, L Mittlmeier… - Journal of Nuclear …, 2021 - jnm.snmjournals.org
Treatment of advanced metastatic castration-resistant prostate cancer after failure of
approved therapy options remains challenging. Prostate-specific membrane antigen (PSMA)–…

Image-guided, tumor stroma-targeted 131I therapy of hepatocellular cancer after systemic mesenchymal stem cell-mediated NIS gene delivery

…, N Wunderlich, D Draganovici, C Zach, FJ Gildehaus… - Molecular Therapy, 2011 - cell.com
Due to its dual role as reporter and therapy gene, the sodium iodide symporter (NIS) allows
noninvasive imaging of functional NIS expression by 123 I-scintigraphy or 124 I-PET imaging …