Neural Wiskott-Aldrich syndrome protein (N-WASP) 1 functions in several intracellular events
including filopodium formation 2 , vesicle transport 3 and movement of Shigella frexneri 4 , …

Malignant cancer cells utilize their intrinsic migratory ability to invade adjacent tissues and
the vasculature, and ultimately to metastasize. Cell migration is the sum of multi-step …

Invasion of cancer cells into surrounding tissue and the vasculature is an initial step in
tumor metastasis. This requires chemotactic migration of cancer cells, steered by protrusive …

We determined the immunohistochemical distributions of orexin-A and orexin-B, hypothalamic
peptides that function in the regulation of feeding behavior and energy homeostasis. …

Invadopodia are actin-rich membrane protrusions with a matrix degradation activity formed
by invasive cancer cells. We have studied the molecular mechanisms of invadopodium …

Ghrelin, an acylated peptide produced predominantly in the stomach, stimulates feeding and
GH secretion via interactions with the GH secretagogue type 1a receptor (GHS-R1a), the …

Invadopodia are matrix-degrading membrane protrusions in invasive carcinoma cells. The
mechanisms regulating invadopodium assembly and maturation are not understood. We …

Cell migration through the extracellular matrix (ECM) is necessary for cancer cells to invade
adjacent tissues and metastasize to an organ distant from primary tumors. Highly invasive …

The spread of cancer during metastatic disease requires that tumor cells subvert normal
regulatory networks governing cell motility to invade surrounding tissues and migrate toward …

Invadopodia are extracellular matrix–degrading protrusions formed by invasive cancer cells
that are thought to function in cancer invasion. Although many invadopodia components …