[HTML][HTML] Integrative analysis of 111 reference human epigenomes

A Kundaje, W Meuleman, J Ernst, M Bilenky, A Yen… - Nature, 2015 - nature.com
111 reference epigenomes is very similar to that used by the International Human Epigenome
… that are only available in a subset of epigenomes here. Lastly, an additional 16 histone …

Integrative analysis of reference epigenomes in 20 rice varieties

L Zhao, L Xie, Q Zhang, W Ouyang, L Deng… - Nature …, 2020 - nature.com
… on epigenome profile (Supplementary Table 2). We further generated datasets for genome-wide
DNA methylation, open … the epigenomes of 20 rice varieties for downstream analyses (…

Integrative analysis of 111 reference human epigenomes

… Integrative analysis coordination Kundaje Anshul 1 2 3 … - Nature, 2015 - nature.com
111 reference epigenomes is very similar to that used by the International Human Epigenome
… that are only available in a subset of epigenomes here. Lastly, an additional 16 histone …

Regulatory genomic circuitry of human disease loci by integrative epigenomics

CA Boix, BT James, YP Park, W Meuleman, M Kellis - Nature, 2021 - nature.com
… Here we overcome many of these limitations and present a new human epigenome
reference, EpiMap (for epigenome integration across multiple annotation projects) (Fig. 1a). We …

The epigenomic landscape of transposable elements across normal human development and anatomy

EC Pehrsson, MNK Choudhary, V Sundaram… - Nature …, 2019 - nature.com
… Overall, 18–31% of human transcription start sites derive from TEs 15,16 , 35% of which
have highly restricted temporal and spatial expression, and 44% of open chromatin regions …

Universal annotation of the human genome through integration of over a thousand epigenomic datasets

H Vu, J Ernst - Genome biology, 2022 - Springer
… Genome-wide maps of histone modifications, histone variants, and open chromatin provide
… modifications or DNase-seq to map open chromatin—can facilitate our understanding of …

Integrative analysis of omics summary data reveals putative mechanisms underlying complex traits

Y Wu, J Zeng, F Zhang, Z Zhu, T Qi, Z Zheng… - Nature …, 2018 - nature.com
… In this study, we report an integrative analysis of summary statistics from GWAS, eQTL
and mQTL studies of the largest sample sizes to date. We mapped 7858 DNAm sites to 2733 …

Epigenomic footprints across 111 reference epigenomes reveal tissue-specific epigenetic regulation of lincRNAs

V Amin, RA Harris, V Onuchic, AR Jackson… - Nature …, 2015 - nature.com
… To address these open questions, we here examine epigenomic footprints of … Data analysis
for this paper utilized 111 reference epigenomes within Release 9 of the Human Epigenome

Integrative analysis of 10,000 epigenomic maps across 800 samples for regulatory genomics and disease dissection

CB Adsera, YP Park, W Meuleman, M Kellis - BioRxiv, 2019 - biorxiv.org
reference of the human epigenome, EpiMap, by incorporation of 1698 new datasets across
three consortia, joint uniform re-processing of a total of 3030 reference … previous reference

Epigenetic patterns in a complete human genome

A Gershman, MEG Sauria, X Guitart, MR Vollger… - Science, 2022 - science.org
… Our study opens these regions to explore their epigenome, leaving no region of the
genome unreachable. Here, with the combination of a complete genome assembly and …