Objective To examine whether plasma neurofilament light chain (NfL) levels were associated
with motor and cognitive progression in Parkinson disease (PD). Methods This prospective …

Neurofibrillary tangles are associated with cognitive dysfunction, and hippocampal atrophy
with increased CSF tau markers. However, the plasma tau levels of Alzheimer's disease (AD) …

Objective α-Synuclein is critical to the pathogenesis of Parkinson’s disease (PD). Few
studies examined the plasma levels of α-synuclein due to the exceptionally low level of α-…

Magnetic nanoparticles biofunctionalized with antibodies against β-amyloid-40 (Aβ-40) and
Aβ-42, which are promising biomarkers related to Alzheimer’s disease (AD), were …

Background It is difficult to discriminate healthy subjects and patients with Parkinson disease
(PD) or Parkinson disease dementia (PDD) by assaying plasma α-synuclein because the …

Background: Changes in β-amyloids (Aβ) and tau proteins have been noted in patients with
Alzheimer’s disease (AD) and patients with both Down syndrome (DS) and AD. However, …

Objective: Parkinson’s disease (PD) has significant clinical overlaps with atypical parkinsonism
syndromes (APS), which have a poorer treatment response and a more aggressive …

Background Active targeting by specific antibodies combined with nanoparticles is a promising
technology for cancer imaging and detection by magnetic resonance imaging (MRI). The …

Previous studies have typically indicated that only one composition factor, such as wick
structures or working fluids, affects the thermal resistance or critical heat flux of heat pipes. In this …

… Jen-Jie Chieh conceived and designed the experiments and wrote the manuscript; Shu-Hsien
Liao designed the SQUID and electronics; Hsin-Hsein Chen, Yen-Fu Lee, and Feng-…