With the success of large-scale visual-language pretraining models and the wide application of image-text retrieval in industry areas, reducing the model size and streamlining their terminal-device deployment have become urgently necessary. The mainstream model structures for image-text retrieval are single-stream and dual-stream, both aiming to close the semantic gap between visual and textual modalities. Dual-stream models excel at offline indexing and fast inference, while single-stream models achieve more accurate cross-model alignment by employing adequate feature fusion. We propose a multi-teacher cross-modality alignment distillation (MCAD) technique to integrate the advantages of single-stream and dual-stream models. By incorporating the fused single-stream features into the image and text features of the dual-stream model, we formulate new modified teacher features and logits. Then, we conduct both logit and feature distillation to boost the capability of the student dual-stream model, achieving high retrieval performance without increasing inference complexity. Extensive experiments demonstrate the remarkable performance and high efficiency of MCAD on image-text retrieval tasks. Furthermore, we implement a mobile CLIP model on Snapdragon clips with only 93M running memory and 30ms search latency, without apparent performance degradation of the original large CLIP.