User profiles for Maria Manich
![]() | Maria ManichInstitut Pasteur Verified email at pasteur.fr Cited by 620 |
Botulinum neurotoxins A and E undergo retrograde axonal transport in primary motor neurons
The striking differences between the clinical symptoms of tetanus and botulism have been
ascribed to the different fate of the parental neurotoxins once internalised in motor neurons. …
ascribed to the different fate of the parental neurotoxins once internalised in motor neurons. …
4D live imaging and computational modeling of a functional gut-on-a-chip evaluate how peristalsis facilitates enteric pathogen invasion
Physical forces are essential to biological function, but their impact at the tissue level is not
fully understood. The gut is under continuous mechanical stress because of peristalsis. To …
fully understood. The gut is under continuous mechanical stress because of peristalsis. To …
Fibronectin induces a transition from amoeboid to a fan morphology and modifies migration in Entamoeba histolytica
M Manich, P Bochet, A Boquet-Pujadas, T Rose… - PLoS …, 2024 - journals.plos.org
Cell migration modes can vary, depending on a number of environmental and intracellular
factors. The high motility of the pathogenic amoeba Entamoeba histolytica is a decisive factor …
factors. The high motility of the pathogenic amoeba Entamoeba histolytica is a decisive factor …
Morphodynamics of the Actin-Rich Cytoskeleton in Entamoeba histolytica
M Manich, N Hernandez-Cuevas… - Frontiers in cellular …, 2018 - frontiersin.org
Entamoeba histolytica is the anaerobic protozoan parasite responsible for human amoebiasis,
the third most deadly parasitic disease worldwide. This highly motile eukaryotic cell …
the third most deadly parasitic disease worldwide. This highly motile eukaryotic cell …
Clostridium perfringens Delta Toxin Is Sequence Related to Beta Toxin, NetB, and Staphylococcus Pore-Forming Toxins, but Shows Functional Differences
M Manich, O Knapp, M Gibert, E Maier… - PloS one, 2008 - journals.plos.org
Clostridium perfringens produces numerous toxins, which are responsible for severe diseases
in man and animals. Delta toxin is one of the three hemolysins released by a number of C…
in man and animals. Delta toxin is one of the three hemolysins released by a number of C…
[HTML][HTML] Interaction between the two subdomains of the C-terminal part of the botulinum neurotoxin A is essential for the generation of protective antibodies
The botulinum neurotoxin A C-terminal fragment (Hc), which mediates the binding of the
toxin to neuronal cell surface receptors, comprises two subdomains, Hc-N (amino acids 873–…
toxin to neuronal cell surface receptors, comprises two subdomains, Hc-N (amino acids 873–…
Domain adapted multitask learning for segmenting amoeboid cells in microscopy
The method proposed in this paper is a robust combination of multi-task learning and
unsupervised domain adaptation for segmenting amoeboid cells in microscopy. A highlight of this …
unsupervised domain adaptation for segmenting amoeboid cells in microscopy. A highlight of this …
BioFlow: a non-invasive, image-based method to measure speed, pressure and forces inside living cells
Cell motility is governed by a complex molecular machinery that converts physico-chemical
cues into whole-cell movement. Understanding the underlying biophysical mechanisms …
cues into whole-cell movement. Understanding the underlying biophysical mechanisms …
Zika virus inhibits IFN-α response by human plasmacytoid dendritic cells and induces NS1-dependent triggering of CD303 (BDCA-2) signaling
…, B Poirier-Beaudouin, V Seffer, M Manich… - Frontiers in …, 2020 - frontiersin.org
Zika virus (ZIKV) dramatically emerged in French Polynesia and subsequently in the
Americas where it has been associated with severe neurological complications in adults and …
Americas where it has been associated with severe neurological complications in adults and …
Live Cells Imaging and Comparative Phosphoproteomics Uncover Proteins from the Mechanobiome in Entamoeba histolytica
GD Jhingan, M Manich, JC Olivo-Marin… - International Journal of …, 2023 - mdpi.com
Entamoeba histolytica is a protozoan parasite and the causative agent of amoebiasis in
humans. This amoeba invades human tissues by taking advantage of its actin-rich cytoskeleton …
humans. This amoeba invades human tissues by taking advantage of its actin-rich cytoskeleton …