Background: In the United States, Black infants have significantly worse birth outcomes than
do White infants. The cause of these persisting racial disparities remains unexplained. Most …

Background Trastuzumab emtansine (T-DM1) is an antibody–drug conjugate incorporating
the human epidermal growth factor receptor 2 (HER2)–targeted antitumor properties of …

Background A previous analysis in this trial showed that among patients with severe,
symptomatic aortic stenosis who were at low surgical risk, the rate of the composite end point of …

Autism spectrum disorder (ASD) is a set of complex neurodevelopment disorders that include
autistic disorder, Asperger disorder, and pervasive developmental disorder not otherwise …

Background The risk of cardiovascular disease is increased among persons with human
immunodeficiency virus (HIV) infection, so data regarding primary prevention strategies in this …

Androgen receptor (AR) belongs to the steroid hormone nuclear receptor superfamily. It
functions as an androgen-dependent transcriptional factor that regulates genes for cell …

Objectives : The purpose of this study was to determine whether noninvasive fractional flow
reserve derived from computed tomography (FFR CT ) predicts coronary revascularization …

Background In low surgical risk patients with symptomatic severe aortic stenosis, the
PARTNER 3 (Safety and Effectiveness of the SAPIEN 3 Transcatheter Heart Valve in Low Risk …

During the latter half of the twentieth century, an explosion of research elucidated a growing
number of causes of disease and contributors to health. Biopsychosocial models that …

Background HIV-infected patients have a high risk of myocardial infarction. We aimed to
assess the ability of statin treatment to reduce arterial inflammation and achieve regression of …