Alzheimer’s disease (AD), like other dementias, is characterized by progressive neuronal
loss and neuroinflammation in the brain. The peripheral leukocyte response occurring …

ATP-binding cassette transporter A1 (ABCA1) transporter regulates cholesterol efflux and is
an essential mediator of high-density lipoprotein (HDL) formation. In amyloid precursor …

Recent genetic and proteomic studies demonstrate that clusterin/apolipoprotein-J is associated
with risk, pathology, and progression of Alzheimer's disease (AD). Our main aim was to …

Chronic exposure to arsenic in drinking water, especially in utero or perinatal exposure, can
initiate neurological and cognitive dysfunction, as well as memory impairment. Several …

Neuroinflammation involving macrophages elevates Prostaglandin E 2 , associated with
neuropathic pain. Treatment with non-steroidal anti-inflammatory drugs (NSAIDs) inhibits …

Alzheimer's disease (AD) is a progressive neurodegenerative disorder where definite diagnosis
can only be made postmortem, and for which the most promising peripheral markers of …

We explored the immune neuropathology underlying multi-day relief from neuropathic pain
in a rat model initiated at the sciatic nerve, by using a nanoemulsion-based nanomedicine as …

See Corona and Landreth (doi: 10.1093/awv300 ) for a scientific commentary on this article.
ATP binding cassette transporter A1 (encoded by ABCA1) regulates cholesterol efflux from …

Chronic constriction injury of the sciatic nerve in rats causes peripheral neuropathy leading
to pain-like behaviors commonly seen in humans. Neuropathy is a leading cause of …

Intravenous (IV) administration of agents into the tail vein of rats can be both difficult and
inconsistent. Optimizing tail vein injections is a key part of many experimental procedures where …