User profiles for Nadrian C. Seeman

Nadrian C. Seeman

New York University
Verified email at nyu.edu
Cited by 57349

Nucleic acid junctions and lattices

NC Seeman - Journal of theoretical biology, 1982 - Elsevier
It is possible to generate sequences of oligomeric nucleic acids which will preferentially
associate to form migrationally immobile junctions, rather than linear duplexes, as they usually …

Synthesis from DNA of a molecule with the connectivity of a cube

J Chen, NC Seeman - Nature, 1991 - nature.com
A PRINCIPAL goal of biotechnology is the assembly of novel biomaterials for analytical,
industrial and therapeutic purposes. The advent of stable immobile nucleic acid branched …

DNA in a material world

NC Seeman - Nature, 2003 - nature.com
The specific bonding of DNA base pairs provides the chemical foundation for genetics. This
powerful molecular recognition system can be used in nanotechnology to direct the …

Design and self-assembly of two-dimensional DNA crystals

E Winfree, F Liu, LA Wenzler, NC Seeman - Nature, 1998 - nature.com
Molecular self-assembly presents a ‘bottom-up’ approach to the fabrication of objects specified
with nanometre precision. DNA molecular structures and intermolecular interactions are …

DNA double-crossover molecules

TJ Fu, NC Seeman - Biochemistry, 1993 - ACS Publications
Revised Manuscript Received January 8, 1993 abstract: DNA molecules containing two
crossover sites between helical domainshave been suggested as intermediates in …

Nanomaterials based on DNA

NC Seeman - Annual review of biochemistry, 2010 - annualreviews.org
The combination of synthetic stable branched DNA and sticky-ended cohesion has led to
the development of structural DNA nanotechnology over the past 30 years. The basis of this …

A precisely controlled DNA biped walking device

WB Sherman, NC Seeman - Nano letters, 2004 - ACS Publications
We present an experimental realization of a molecular walking motor built from DNA. The
device consists of a biped and a well-defined track where it walks. Input DNA strands act as a …

Nucleic acid nanostructures and topology

NC Seeman - Angewandte Chemie International Edition, 1998 - Wiley Online Library
Knots, polyhedra, and Borromean rings with specific structural and topological features can
be made from DNA. Biotechnologists have been exploiting the programmability of DNA …

De Novo Design of Sequences for Nucleic Acid Structural Engineering

NC Seeman - Journal of biomolecular structure and dynamics, 1990 - Taylor & Francis
An interactive procedure has been developed to assign sequences for the design of nucleic
acid secondary structure. The primary goal of the procedure is to facilitate macromolecular …

A bipedal DNA Brownian motor with coordinated legs

T Omabegho, R Sha, NC Seeman - science, 2009 - science.org
A substantial challenge in engineering molecular motors is designing mechanisms to coordinate
the motion between multiple domains of the motor so as to bias random thermal motion. …