Monoclonal gammopathy of undetermined significance (MGUS) is a premalignant plasma-cell
proliferative disorder associated with a life-long risk of progression to multiple myeloma (…

Background Tobacco smoking is responsible for over 90% of lung cancer cases, and yet the
precise molecular alterations induced by smoking in lung that develop into cancer and …

Three genetic loci for lung cancer risk have been identified by genome-wide association
studies (GWAS), but inherited susceptibility to specific histologic types of lung cancer is not well …

Although several lung cancer susceptibility loci have been identified, much of the heritability
for lung cancer remains unexplained. Here 14,803 cases and 12,262 controls of European …

Genome‐wide scans of nucleotide variation in human subjects are providing an increasing
number of replicated associations with complex disease traits. Most of the variants detected …

Background In the National Lung Screening Trial (NLST), screening with low-dose computed
tomography (CT) resulted in a 20% reduction in lung-cancer mortality among participants …

The incidence and mortality rates of prostate cancer are significantly higher in African-American
men when compared with European-American men. We tested the hypothesis that …

We conducted imputation to the 1000 Genomes Project of four genome-wide association
studies of lung cancer in populations of European ancestry (11,348 cases and 15,861 controls) …

Background Otherwise healthy persons with a small number of B-cell clones circulating in
the peripheral blood have been designated as having monoclonal B-cell lymphocytosis (MBL)…

Purpose: The molecular drivers that determine histology in lung cancer are largely unknown.
We investigated whether microRNA (miR) expression profiles can differentiate histologic …