We study the problem of computing ad-hoc selective families: Given a collection of subsets of [n] = {1,2,...,n}, a selective family for is a collection of subsets of [n] such that for any F ∈ there exists S ∈ such that |F ∩ S|=1. We first provide a polynomial-time algorithm that, for any instance , returns a selective family of size O((1+ log(△ _max /△ _min )) · log || ) where ∏_max and ∏_min denote the maximal and the minimal size of a subset in , respectively. This result is applied to the problem of broadcasting in radio networks with known topology. We indeed develop a broadcasting protocol which completes any broadcast operation within O(D log ∏ log n/D) time-slots, where n, D and ∏ denote the number of nodes, the maximal eccentricity, and the maximal in-degree of the network, respectively. Finally, we consider the combinatorial optimization problem of computing broadcasting protocols with minimal completion time and we prove some hardness results regarding the approximability of this problem.