This paper examines the quality assessment of video streaming applications in a heterogeneous wireless environment, where the user hands off across inter-technology radio access networks. Three different scenarios have been considered: scenario with seamless handover using the media handover framework to initiate handover, seamless handoff combined with rate adaptation that is based on Rate-Distortion and seamless handoff with rate adaptation that is optimized using network bandwidth and packet loss parameters. The results from two video sequences have shown that both objective quality evaluation and the subjective evaluation (double stimulus- SDSCE, DSCQS) are optimized under the combined seamless handover and rate adaptation functionalities.