PECC: Correcting contigs based on paired-end read distribution
Motivation Cheap and fast next generation sequencing (NGS) technologies facilitate
research of de novo assembly greatly. The reliability of contigs is critical to construct reliable
scaffolding. However, contigs generated from most assemblers contain errors because of
the limitation of assembly strategy and computation complexity. Among all these errors, the
misassembly error is one of the most harmful types. Results In this paper, we propose a new
method named “PECC” to identify and correct misassembly errors in contigs based on the …
research of de novo assembly greatly. The reliability of contigs is critical to construct reliable
scaffolding. However, contigs generated from most assemblers contain errors because of
the limitation of assembly strategy and computation complexity. Among all these errors, the
misassembly error is one of the most harmful types. Results In this paper, we propose a new
method named “PECC” to identify and correct misassembly errors in contigs based on the …
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