Dorsomorphin inhibits BMP signals required for embryogenesis and iron metabolism
Bone morphogenetic protein (BMP) signals coordinate developmental patterning and have
essential physiological roles in mature organisms. Here we describe the first known small-…
essential physiological roles in mature organisms. Here we describe the first known small-…
Selective enhancement of endothelial BMPR-II with BMP9 reverses pulmonary arterial hypertension
…, SD Moore, KM Drake, MA Aldred, PB Yu… - Nature medicine, 2015 - nature.com
Genetic evidence implicates the loss of bone morphogenetic protein type II receptor (BMPR-II)
signaling in the endothelium as an initiating factor in pulmonary arterial hypertension (PAH…
signaling in the endothelium as an initiating factor in pulmonary arterial hypertension (PAH…
BMP type I receptor inhibition reduces heterotopic ossification
Fibrodysplasia ossificans progressiva (FOP) is a congenital disorder of progressive and
widespread postnatal ossification of soft tissues 1 , 2 , 3 , 4 and is without known effective …
widespread postnatal ossification of soft tissues 1 , 2 , 3 , 4 and is without known effective …
CMOS resistive fuses for image smoothing and segmentation
PC YU, SJ Decker, HS Lee, CG Sodini… - IEICE Transactions on …, 1992 - search.ieice.org
A two-terminal nonlinear element called a resistive fuse is described. Its application in image
smoothing and segmentation is explained. Two types CMOS resistive fuses were designed, …
smoothing and segmentation is explained. Two types CMOS resistive fuses were designed, …
FGF signaling inhibition in ESCs drives rapid genome-wide demethylation to the epigenetic ground state of pluripotency
Genome-wide erasure of DNA methylation takes place in primordial germ cells (PGCs) and
early embryos and is linked with pluripotency. Inhibition of Erk1/2 and Gsk3β signaling in …
early embryos and is linked with pluripotency. Inhibition of Erk1/2 and Gsk3β signaling in …
High electron mobility InAs nanowire field‐effect transistors
Single‐crystal InAs nanowires (NWs) are synthesized using metal–organic chemical vapor
deposition (MOCVD) and fabricated into NW field‐effect transistors (NWFETs) on a SiO 2 /n + …
deposition (MOCVD) and fabricated into NW field‐effect transistors (NWFETs) on a SiO 2 /n + …
[BOOK][B] The electronics handbook
…, HE Young, J Pierre, I Bordelon, S Felder, PKL Yu… - 2018 - taylorfrancis.com
During the ten years since the appearance of the groundbreaking, bestselling first edition of
The Electronics Handbook, the field has grown and changed tremendously. With a focus on …
The Electronics Handbook, the field has grown and changed tremendously. With a focus on …
ACVR1R206H receptor mutation causes fibrodysplasia ossificans progressiva by imparting responsiveness to activin A
…, CJ Schoenherr, K Feeley, PB Yu… - Science translational …, 2015 - science.org
Fibrodysplasia ossificans progressiva (FOP) is a rare genetic disorder characterized by
episodically exuberant heterotopic ossification (HO), whereby skeletal muscle is abnormally …
episodically exuberant heterotopic ossification (HO), whereby skeletal muscle is abnormally …
Data resource profile: accessible resource for integrated epigenomic studies (ARIES)
ARIES is a population-based resource of DNA methylation data accessible by the research
community, established with the aim of improving our understanding of the determinants and …
community, established with the aim of improving our understanding of the determinants and …
Inhibition of bone morphogenetic protein signaling reduces vascular calcification and atherosclerosis
…, JS Seehra, WM Zapol, KD Bloch, PB Yu - … , and vascular biology, 2012 - ahajournals.org
Objective— The expression of bone morphogenetic proteins (BMPs) is enhanced in human
atherosclerotic and calcific vascular lesions. Although genetic gain- and loss-of-function …
atherosclerotic and calcific vascular lesions. Although genetic gain- and loss-of-function …