PDZBase is a database that aims to contain all known PDZ-domain-mediated protein–protein
interactions. Currently, PDZBase contains approximately 300 such interactions, which …

Childhood posterior fossa (PF) ependymomas cause substantial morbidity and mortality.
These tumors lack recurrent genetic mutations, but a subset of these ependymomas exhibits …

Neuroendocrine (NE) prostate cancer (NEPC) is a lethal subtype of castration-resistant prostate
cancer (PCa) arising either de novo or from transdifferentiated prostate adenocarcinoma …

Previous work from this laboratory indicates a role for the complement component C5 in
neuroprotection against excitotoxicity. In the present study, we tested the hypothesis that the C5‐…

Purpose: To compare gene expression profiles of chromophobe renal cell carcinoma (RCC)
and benign oncocytoma, aiming at identifying differentially expressed genes. Experimental …

Background The complement system is thought to be involved in the pathogenesis of
numerous neurological diseases. We previously reported that pre-treatment of murine cortico-…

We previously reported that pretreatment of murine cortico‐hippocampal neuronal cultures
with the complement‐derived anaphylatoxin C5a, protects against glutamate neurotoxicity. In …

There is evidence that the complement system, a major component of inflammatory responses,
may play an important role in neurodegenerative conditions such as Alzheimer’s disease …

In addition to being causally linked to the formation of multiple tumor types, tobacco use has
been associated with decreased efficacy of anticancer treatment and reduced survival time. …

Background Immune cell expression profiling from patient samples is critical for the successful
development of immuno-oncology agents and is useful to understand mechanism-of-…