An Experimentally Validated Genome-Scale Metabolic Reconstruction of Klebsiella pneumoniae MGH 78578, iYL1228

YC Liao, TW Huang, FC Chen, P Charusanti… - Journal of …, 2011 - Am Soc Microbiol
… Although the difference was reduced to 20.1% (65 out of 323) after validation of the consensus
Biolog result obtained from the two data sets with our experimental result for MGH 78578, …

Network-Based Metabolism-Centered Screening of Potential Drug Targets in Klebsiella pneumoniae at Genome Scale

MF Cesur, B Siraj, R Uddin, S Durmuş… - Frontiers in cellular and …, 2020 - frontiersin.org
… the network topology of the reconstructed GMN to prioritize drug targets in combination with
genomic… In this regard, we investigated metabolic pathways in KEGG and BioCyc databases

Comparative genomic reconstruction of transcriptional regulatory networks in bacteria

DA Rodionov - Chemical reviews, 2007 - ACS Publications
… in two Erwinia species and Klebsiella pneumoniae also include the rhiT-… reconstruction of
metabolic pathways from genomic data have led to the development of metabolic databases

The Capsule Regulatory Network of Klebsiella pneumoniae Defined by density-TraDISort

MJ Dorman, T Feltwell, DA Goulding, J Parkhill… - MBio, 2018 - Am Soc Microbiol
… of capsule regulatory genes are located in the core genome. … pneumoniae were identified,
and we use these data to … Complementation caused a complete restoration of wild-type …

Genomic reconstruction of transcriptional regulatory networks in lactic acid bacteria

DA Ravcheev, AA Best, NV Sernova, MD Kazanov… - BMC genomics, 2013 - Springer
reconstructed in the studied genomes (Additional file5). Initially we collected the published
experimental data on transcriptional regulation … availability of experimental data, we applied …

Exploring the metabolic network of the epidemic pathogen Burkholderia cenocepacia J2315 via genome-scale reconstruction

K Fang, H Zhao, C Sun, CMC Lam, S Chang… - BMC systems …, 2011 - Springer
… We reconstructed the genome-scale metabolic network of B. cenocepacia J2315. An iterative
reconstruction … cenocepacia J2315 from the public biological databases. Careful effort was …

Metabolic diversity of the emerging pathogenic lineages of Klebsiella pneumoniae

C Blin, V Passet, M Touchon… - Environmental …, 2017 - Wiley Online Library
genomic and phenotypic analysis of a diverse set of K. … the regulatory networks of the
strains, or to some redundancy in … We used IQ-TREE version 1.2.3 to reconstruct the maximum …

An integrative, multi-omics approach towards the prioritization of Klebsiella pneumoniae drug targets

PIP Ramos, D Fernandez Do Porto, E Lanzarotti… - Scientific reports, 2018 - nature.com
… of a multidimensional data integration strategy in order to prioritize drug targets in K. … validated
in silico genome-scale metabolic reconstruction available for K. pneumoniae MGH 78578 …

[PDF][PDF] The capsule regulatory network of Klebsiella pneumoniae defined by density-TraDISort. mBio 9: e01863-18

MJ Dorman, T Feltwell, DA Goulding, J Parkhill… - 2018 - research-management.mq.edu.au
… tory genes are located in the core genome. Overall, our findings … pneumoniae were identified,
and we use these data to … Complementation caused a complete restoration of wild-type …

Novel antimicrobial development using genome-scale metabolic model of Gram-negative pathogens: a review

WY Chung, Y Zhu, MH Mahamad Maifiah… - The Journal of …, 2021 - nature.com
… of Genes and Genomes [32] and Biocyc [33] databases. The … process of metabolic network
reconstruction from months to a … of Klebsiella pneumoniae drug targets. Sci Rep. 2018;8. …