Image quality assessment (IQA) is a fundamental problem in image processing that aims to measure the objective quality of a distorted image. Traditional full-reference (FR) IQA methods use fixed-size sliding windows to obtain structure information but ignore the variable spatial configuration information. In order to better measure the multi-scale objects, we propose a novel IQA method, named RSEI, based on the perspective of the variable receptive field and information entropy. First, we find that consistence relationship exists between the information fidelity and human visual of individuals. Thus, we reproduce the human visual system (HVS) to semantically divide the image into multiple patches via rectangular-normalized superpixel segmentation. Then the weights of each image patches are adaptively calculated via their information volume. We verify the effectiveness of RSEI by applying it to data from the TID2008 database and denoise algorithms. Experiments show that RSEI outperforms some state-of-the-art IQA algorithms, including visual information fidelity (VIF) and weighted average deep image quality measure (WaDIQaM).