User profiles for Shachi Sharma

Shachi Sharma

South Asian University
Verified email at sau.int
Cited by 398

[HTML][HTML] Referateband: HPV–A different view on Head and Neck Cancer

C Wittekindt, S Wagner, SJ Sharma… - Laryngo-rhino …, 2018 - ncbi.nlm.nih.gov
Head and neck cancer is the sixth most common cancer with over 500000 annually reported
incident cases worldwide. Besides major risk factors tobacco and alcohol, oropharyngeal …

Prognostic implications of p16 and HPV discordance in oropharyngeal cancer (HNCIG-EPIC-OPC): a multicentre, multinational, individual patient data analysis

…, RB de Jong, C Wittekindt, A Quaas, SJ Sharma… - The Lancet …, 2023 - thelancet.com
Background p16 INK4a (p16) immunohistochemistry is the most widely used biomarker assay
for inferring HPV causation in oropharyngeal cancer in clinical and trial settings. However, …

The role of lifelong machine learning in bridging the gap between human and machine learning: A scientometric analysis

M Abulaish, NA Wasi, S Sharma - … Reviews: Data Mining and …, 2024 - Wiley Online Library
Due to advancements in data collection, storage, and processing techniques, machine learning
has become a thriving and dominant paradigm. However, one of its main shortcomings …

Human papillomavirus-related head and neck cancer

S Wagner, SJ Sharma, N Wuerdemann… - Oncology research and …, 2017 - karger.com
Human papillomavirus(HPV)-related head and neck cancer is recognized as a distinct
tumor entity with rising incidence reported for several countries. These tumors arise from …

Prognostic impact of AJCC/UICC 8th edition new staging rules in oropharyngeal squamous cell carcinoma

N Würdemann, S Wagner, SJ Sharma… - Frontiers in …, 2017 - frontiersin.org
Introduction The purpose of this study was to test whether the 8th edition of the AJCC/UICC
TNM staging system (UICC) precisely differentiates between stages and reflects disease …

Human papillomavirus association is the most important predictor for surgically treated patients with oropharyngeal cancer

S Wagner, C Wittekindt, SJ Sharma… - British journal of …, 2017 - nature.com
Background: Upfront surgery is a valuable treatment option for oropharyngeal squamous
cell carcinoma (OPSCC) and risk stratification is emerging for treatment de-escalation in …

Evaluation of p16INK4a expression as a single marker to select patients with HPV-driven oropharyngeal cancers for treatment de-escalation

…, H Reder, A Bushnak, SJ Sharma… - British journal of …, 2020 - nature.com
Background A remarkably better prognosis is associated with oropharyngeal squamous cell
carcinomas (OPSCC) driven by human papillomaviruses (HPV) compared with HPV-…

Predicting HPV association using deep learning and regular H&E stains allows granular stratification of oropharyngeal cancer patients

…, A Charpentier, Y Tolkach, K Brinker, SJ Sharma… - npj Digital …, 2023 - nature.com
Human Papilloma Virus (HPV)-associated oropharyngeal squamous cell cancer (OPSCC)
represents an OPSCC subgroup with an overall good prognosis with a rising incidence in …

Head-to-Head Comparison of [68 Ga]Ga-FAPI-46-PET/CT and [18F]F-FDG-PET/CT for Radiotherapy Planning in Head and Neck Cancer

…, D Akuamoa-Boateng, C Baues, SJ Sharma… - Molecular imaging and …, 2022 - Springer
Introduction In head and neck cancers (HNCs), fibroblast activation protein (FAP) is expressed
by cancer-associated fibroblasts (CAFs) in the tumor microenvironment. Preliminary …

LAG-3, TIM-3 and VISTA Expression on Tumor-Infiltrating Lymphocytes in Oropharyngeal Squamous Cell Carcinoma—Potential Biomarkers for Targeted Therapy …

…, C Wittekindt, CU Huebbers, SJ Sharma… - International journal of …, 2020 - mdpi.com
Tumor growth and survival requires a particularly effective immunosuppressant tumor
microenvironment (TME) to escape destruction by the immune system. While immunosuppressive …