Angiopoietin (Ang)-1 and -2 have been recently identified as potent angiogenic factors which
function in concert with vascular endothelial growth factor (VEGF), but no detailed clinical …

Purpose: The purpose is to assess clinical significance of matrix metalloproteinase (MMP)-2
and MMP-9 status, especially MMP-2 status, in stromal cells in non–small-cell lung cancer (…

Purpose The Wnt gene family encodes the multifunctional signaling glycoproteins. We
performed the present study to investigate the clinical significance of Wnt5a expression in non–…

Purpose The nucleoside analogue 3′-deoxy-3′- 18 F-fluorothymidine (FLT) has recently
been introduced for imaging cell proliferation with positron emission tomography (PET). We …

The reversion-inducing–cysteine-rich protein with Kazal motifs (RECK) was initially isolated
as a transformation-suppressor gene by expression cloning and found to encode a …

BACKGROUND: The Wnt gene family is involved in embryogenesis and tumourigenesis.
We investigated the clinical significance of Wnt1 expression in non-small cell lung cancer (…

PURPOSE: The clinical significance of p21 expression remains unclear, whereas many
experimental studies have demonstrated that p21, the product of the WAF1/CIP1/SDI1 gene, …

The Wnt family genes encode multifunctional signaling glycoproteins that are involved in the
regulation of a wide variety of normal and pathological processes including tumorigenesis. …

Purpose The nucleoside analog 3′-deoxy-3′- 18 F-fluorothymidine (FLT) has been
introduced for imaging cell proliferation with positron emission tomography (PET). We …

Purpose: The melanoma differentiation-associated gene-7 (MDA-7) protein, also known as
interleukin (IL)-24, is a novel candidate of tumor suppressor that can induce apoptosis …