Acute stimulation of cardiac β1-adrenergic receptors (β1ARs) by norepinephrine represents
the strongest endogenous mechanism for increasing cardiac function, but long-term …

Background—Considerable controversy exists regarding impairment of cardiac function in
diabetes mellitus (DM). We investigated the serial changes in left ventricular (LV) …

For over a century, there has been intense debate as to the reason why some cardiac
stresses are pathological and others are physiological. One long-standing theory is that …

Background— The presence of chronic kidney disease is a significant independent risk
factor for poor prognosis in patients with chronic heart failure. However, the mechanisms and …

The objectives of the present study were (1) to determine whether oxidized low-density
lipoprotein (LDL) and lysophosphatidylcholine (lyso-PC), a major phospholipid component of …

Vascular and cardiac valve calcification is associated with cardiovascular mortality in the
general population. Increasing clinical and experimental evidence suggests that inflammation …

Regulatory T cells (Tregs) play a crucial role in the negative regulation of immune responses.
Recent studies suggest that Tregs are involved in the pathogenesis of atherosclerosis and …

Vascular endothelial growth factor-A (VEGF-A) released from adipocytes promotes angiogenesis;
and thereby ameliorates the local hypoxia-induced adipose inflammation and insulin …

Objectives : We examined whether ultrasonic microbubble destruction (US/MB) enables
therapeutic myocardial gene transfer of hepatocyte growth factor (HGF) for acute myocardial …

Although visit-to-visit variability in systolic blood pressure (SBP) has recently been demonstrated
to be a strong predictor of stroke, there are no data about relationships between SBP …