User profiles for Thomas O’Brien
![]() | Tom O'BrienStaff research scientist, Google Quantum AI Verified email at google.com Cited by 8605 |
Prolonged extracorporeal oxygenation for acute post-traumatic respiratory failure (shock-lung syndrome) use of the Bramson membrane lung
JD Hill, TG O'Brien, JJ Murray, L Dontigny… - … England Journal of …, 1972 - Mass Medical Soc
A 24-year-old man sustained subadventitial transection of the thoracic aorta and multiple
orthopedic injuries resulting from blunt trauma. The aortic injury was repaired. Because …
orthopedic injuries resulting from blunt trauma. The aortic injury was repaired. Because …
A variant upstream of IFNL3 (IL28B) creating a new interferon gene IFNL4 is associated with impaired clearance of hepatitis C virus
…, DL Thomas, B Rehermann, RP Donnelly, TR O'Brien - Nature …, 2013 - nature.com
Chronic infection with hepatitis C virus (HCV) is a common cause of liver cirrhosis and cancer.
We performed RNA sequencing in primary human hepatocytes activated with synthetic …
We performed RNA sequencing in primary human hepatocytes activated with synthetic …
Serum HIV-1 RNA levels and time to development of AIDS in the Multicenter Hemophilia Cohort Study
TR O'Brien, WA Blattner, D Waters, ME Eyster… - Jama, 1996 - jamanetwork.com
Objective. —To determine if the long-term incidence of the acquired immunodeficiency
syndrome (AIDS) is related to human immunodeficiency virus type 1 (HIV-1) RNA levels …
syndrome (AIDS) is related to human immunodeficiency virus type 1 (HIV-1) RNA levels …
Quantum error mitigation
For quantum computers to successfully solve real-world problems, it is necessary to tackle
the challenge of noise: the errors that occur in elementary physical components due to …
the challenge of noise: the errors that occur in elementary physical components due to …
MFIX documentation theory guide
This report describes the MFIX (Multiphase Flow with Interphase exchanges) computer model.
MFIX is a general-purpose hydrodynamic model that describes chemical reactions and …
MFIX is a general-purpose hydrodynamic model that describes chemical reactions and …
Contrasting Genetic Influence of CCR2 and CCR5 Variants on HIV-1 Infection and Disease Progression
…, GA Huttley, DA Lomb, JJ Goedert, TR O'Brien… - Science, 1997 - science.org
The critical role of chemokine receptors (CCR5 and CXCR4) in human immunodeficiency
virus–type 1 (HIV-1) infection and pathogenesis prompted a search for polymorphisms in other …
virus–type 1 (HIV-1) infection and pathogenesis prompted a search for polymorphisms in other …
Relative resistance to HIV–1 infection of CD4 lymphocytes from persons who remain uninfected despite multiple high–risk sexual exposures
WA Paxton, SR Martin, D Tse, TR O'Brien, J Skurnick… - Nature medicine, 1996 - nature.com
Some individuals remain uninfected with human immunodeficiency virus type–1 (HIV–1)
despite multiple high–risk sexual exposures. We studied a cohort of 25 subjects with histories of …
despite multiple high–risk sexual exposures. We studied a cohort of 25 subjects with histories of …
Antimicrobial resistance in developing countries. Part I: recent trends and current status
The global problem of antimicrobial resistance is particularly pressing in developing countries,
where the infectious disease burden is high and cost constraints prevent the widespread …
where the infectious disease burden is high and cost constraints prevent the widespread …
Genetic Acceleration of AIDS Progression by a Promoter Variant of CCR5
…, TR O'Brien, MW Hilgartner, D Vlahov, SJ O'Brien… - Science, 1998 - science.org
The CCR5 gene encodes a cell surface chemokine receptor molecule that serves as the
principal coreceptor, with CD4, for macrophage-tropic (R5) strains of human immunodeficiency …
principal coreceptor, with CD4, for macrophage-tropic (R5) strains of human immunodeficiency …
Genetic restriction of AIDS pathogenesis by an SDF-1 chemokine gene variant
…, S Buchbinder, E Vittinghoff, JJ Goedert, TR O'Brien… - Science, 1998 - science.org
Stromal-derived factor (SDF-1) is the principal ligand for CXCR4, a coreceptor with CD4 for
T lymphocyte cell line–tropic human immunodeficiency virus–type 1 (HIV-1). A common …
T lymphocyte cell line–tropic human immunodeficiency virus–type 1 (HIV-1). A common …