Recently, the Blockchain-based cryptocurrency market witnessed enormous growth. Bitcoin, the leading cryptocurrency, reached all-time highs many times over the year leading to speculations to explain the trend in its growth. In this article, we study Bitcoin and Ethereum and explore features in their network that explain their price hikes. We gather data and analyze user and network activity that highly impact the price of these cryptocurrencies. We monitor the change in the activities over time and relate them to economic theories. We identify key network features that help us to determine the demand and supply dynamics in a cryptocurrency. Finally, we use machine learning methods to construct models that predict Bitcoin price. Based on our experimental results using two large datasets for validation, we confirm that our approach provides an accuracy of up to 99% for Bitcoin and Ethereum price prediction in both instances.