Selective autophagy of intracellular organelles: recent research advances

W Li, P He, Y Huang, YF Li, J Lu, M Li… - …, 2021 - pmc.ncbi.nlm.nih.gov
Macroautophagy (hereafter called autophagy) is a highly conserved physiological process
that degrades over-abundant or damaged organelles, large protein aggregates and invading …

ALOX15-launched PUFA-phospholipids peroxidation increases the susceptibility of ferroptosis in ischemia-induced myocardial damage

…, WJ Duan, G Wang, H Kurihara, RR He, YF Li… - Signal transduction and …, 2022 - nature.com
Myocardial ischemia/reperfusion (I/R) injury is a classic type of cardiovascular disease
characterized by injury to cardiomyocytes leading to various forms of cell death. It is believed that …

Midbrain dopamine oxidation links ubiquitination of glutathione peroxidase 4 to ferroptosis of dopaminergic neurons

J Sun, XM Lin, DH Lu, M Wang, K Li, SR Li, ZQ Li… - The Journal of clinical …, 2023 - jci.org
Parkinson’s disease (PD) is a neurodegenerative disorder characterized by the gradual loss
of midbrain dopaminergic neurons in association with aggregation of α-synuclein. Oxidative …

Oxygenated phosphatidylethanolamine navigates phagocytosis of ferroptotic cells by interacting with TLR2

…, HB Gong, HY Gao, YP Wu, WY Sun, ZQ Li… - Cell Death & …, 2021 - nature.com
During cancer therapy, phagocytic clearance of dead cells plays a vital role in immune
homeostasis. The nonapoptotic form of cell death, ferroptosis, exhibits extraordinary potential in …

Caffeine protects skin from oxidative stress-induced senescence through the activation of autophagy

YF Li, SH Ouyang, LF Tu, X Wang, WL Yuan… - …, 2018 - pmc.ncbi.nlm.nih.gov
Skin cells are vulnerable to oxidative stress-induced senescence, which may lead to abnormal
aging or aging-related disorders. Therefore, strategies that can ameliorate oxidative stress…

Cardiolipin and its different properties in mitophagy and apoptosis

XX Li, B Tsoi, YF Li, H Kurihara… - … of Histochemistry & …, 2015 - journals.sagepub.com
Cardiolipin (CL) is a unique dimeric phospholipid that exists almost exclusively in the inner
mitochondrial membrane (IMM) in eukaryotic cells. Two chiral carbons and four fatty acyl …

Enhanced therapeutic efficacy of doxorubicin for breast cancer using chitosan oligosaccharide-modified halloysite nanotubes

J Yang, Y Wu, Y Shen, C Zhou, YF Li… - ACS applied materials …, 2016 - ACS Publications
Halloysite nanotubes (HNTs) are natural aluminosilicates with unique hollow lumen structure,
also having high specific area, good biocompatibility, nontoxicity, and low price. Here, we …

[HTML][HTML] ALOX5 inhibition protects against dopaminergic neurons undergoing ferroptosis

K Li, M Wang, ZH Huang, M Wang, WY Sun… - Pharmacological …, 2023 - Elsevier
Oxidative disruption of dopaminergic neurons is regarded as a crucial pathogenesis in
Parkinson's disease (PD), eventually causing neurodegenerative progression. (-)-Clausenamide (…

A new mechanism of vitamin C effects on A/FM/1/47 (H1N1) virus‐induced pneumonia in restraint‐stressed mice

Y Cai, YF Li, LP Tang, B Tsoi, M Chen… - BioMed Research …, 2015 - Wiley Online Library
It is well known that vitamin C could protect against influenza infection, but little is known about
the mechanisms. This study aimed to investigate the influence and possible mechanisms …

Interleukin-17, produced by lymphocytes, promotes tumor growth and angiogenesis in a mouse model of breast cancer

JW Du, KY Xu, LY Fang, XL Qi - Molecular medicine …, 2012 - spandidos-publications.com
Previous studies have suggested that interleukin-17 (IL-17), an inflammatory cytokine expressed
predominantly by Th17 cells, is highly expressed in tumor tissue and may help tumors …