User profiles for Zhongwen Chen

Zhongwen Chen

Interdisciplinary Research Center on Biology and Chemistry, Chinese Academy of Sciences
Verified email at sioc.ac.cn
Cited by 1689

Dual enzyme-like activities of iron oxide nanoparticles and their implication for diminishing cytotoxicity

Z Chen, JJ Yin, YT Zhou, Y Zhang, L Song, M Song… - ACS …, 2012 - ACS Publications
Iron oxide nanoparticles (IONPs) are frequently used in biomedical applications, yet their
toxic potential is still a major concern. While most studies of biosafety focus on cellular …

EGFR family and Src family kinase interactions: mechanics matters?

Z Chen, D Oh, AK Dubey, M Yao, B Yang… - Current opinion in cell …, 2018 - Elsevier
Receptor tyrosine kinases (RTKs), such as the EGF receptor family, and adhesion molecules,
such as integrins, have historically been viewed to have distinctly separable roles in the …

Silver nanoparticles: a novel radiation sensitizer for glioma?

P Liu, Z Huang, Z Chen, R Xu, H Wu, F Zang, C Wang… - Nanoscale, 2013 - pubs.rsc.org
Malignant gliomas are the most common primary intracranial tumors with a dismal prognosis.
Previous investigations by our group demonstrated the radiosensitizing effect of silver …

A palmitoylation–depalmitoylation relay spatiotemporally controls GSDMD activation in pyroptosis

…, Y Yang, H Shan, S Hou, H Fang, M Ma, Z Chen… - Nature Cell …, 2024 - nature.com
Gasdermin D (GSDMD) is the executor of pyroptosis, which is important for host defence
against pathogen infection. Following activation, caspase-mediated cleavage of GSDMD …

Integrin-beta3 clusters recruit clathrin-mediated endocytic machinery in the absence of traction force

…, A Krishnasamy, KH Biswas, A Ravasio, Z Chen… - Nature …, 2015 - nature.com
The turnover of integrin receptors is critical for cell migration and adhesion dynamics. Here
we find that force development at integrins regulates adaptor protein recruitment and …

Research on the relationship between foreign trade and the GDP growth of East China—empirical analysis based on causality

Y Li, Z Chen, C San - Modern Economy, 2010 - publications.articalerewriter.com
In open economy, development of foreign trade greatly impacts GDP growth. Adopt modern
testing methods like unit root, timeseries cointegration analysis and error correction model …

Socioeconomic status and physical activity in Chinese adults: a report from a community-based survey in Jiaxing, China

M Chen, Y Wu, H Narimatsu, X Li, C Wang, J Luo… - PloS one, 2015 - journals.plos.org
Objectives This study examines the associations of socioeconomic status (SES) with
intensity of different types of physical activity (PA) in Chinese adults, aimed at outlining and …

Mechanical activation opens a lipid-lined pore in OSCA ion channels

…, X Ma, S He, L Yuan, Y Wang, W Yang, X Yue, Z Chen… - Nature, 2024 - nature.com
OSCA/TMEM63 channels are the largest known family of mechanosensitive channels 1 , 2
– 3 , playing critical roles in plant 4 , 5 , 6 – 7 and mammalian 8 , 9 mechanotransduction. …

Molecular Identification of Endophytic Fungi and Their Pathogenicity Evaluation Against Dendrobium nobile and Dendrobium officinale

…, X Fan, F Shu, Z Chen, Q Zhou, J Shi, J Chen - International Journal of …, 2020 - mdpi.com
Dendrobium are tropical orchid plants that host diverse endophytic fungi. The role of these
fungi is not currently well understood in Dendrobium plants. We morphologically and …

Graphene oxide-based Fe2O3 hybrid enzyme mimetic with enhanced peroxidase and catalase-like activities

L Song, C Huang, W Zhang, M Ma, Z Chen… - Colloids and Surfaces A …, 2016 - Elsevier
Graphene based materials are widely used in energy conversation and catalytic reaction due
to their rapid electron transfer capacity and large surface area. Herein, graphene Fe 2 O 3 (…