Feroksidaza
(Preusmjereno sa stranice Ceruloplazmin)
| Feroksidaza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 1.16.3.1 | ||||||||
| CAS broj | 104404-69-5&title= 9031-37-2, 104404-69-5 | ||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB | RCSB PDB PDBe PDBj PDBsum | ||||||||
| |||||||||
Feroksidaza (EC 1.16.3.1, ceruloplazmin, feroksidaza I, gvožđe oksidaza, gvožđe(II):kiseonik oksidoreduktaza, fero:O2 oksidoreduktaza, gvožđe II:kiseonik oksidoreduktaza, hefastin, HEPH) je enzim sa sistematskim imenom Fe(II):kiseonična oksidoreduktaza.[1][2][3][4][5] Ovaj enzim katalizuje sledeću hemijsku reakciju
- 4 Fe(II) + 4 H+ + O2 4 Fe(III) + 2 H2O
Enzim u krvnoj plazmi (ceruloplazmin) pripada familiji multibakarnih oksidaza.
- ↑ Osaki, S. (1966). „Kinetic studies of ferrous ion oxidation with crystalline human ferroxidase (ceruloplasmin)”. J. Biol. Chem. 241: 5053-5059. PMID 5925868.
- ↑ Osaki, S. and Walaas, O. (1967). „Kinetic studies of ferrous ion oxidation with crystalline human ferroxidase. II. Rate constants at various steps and formation of a possible enzyme-substrate complex”. J. Biol. Chem. 242: 2653-2657. PMID 6027241.
- ↑ Lindley, P.F. Card, G. Zaitseva, I. Zaitsev, V. Reinhammar, B. SelinLindgren, E. and Yoshida, K. (1997). „An X-ray structural study of human ceruloplasmin in relation to ferroxidase activity”. J. Biol. Inorg. Chem. 2: 454-463.
- ↑ Takai, M., Kamimura, K. and Sugio, T. (2001). „A new iron oxidase from a moderately thermophilic iron oxidizing bacterium strain TI-1”. Eur. J. Biochem. 268: 1653-1658. PMID 11248684.
- ↑ Chen, H., Attieh, Z.K., Su, T., Syed, B.A., Gao, H., Alaeddine, R.M., Fox, T.C., Usta, J., Naylor, C.E., Evans, R.W., McKie, A.T., Anderson, G.J. and Vulpe, C.D. (2004). „Hephaestin is a ferroxidase that maintains partial activity in sex-linked anemia mice”. Blood 103: 3933-3939. PMID 14751926.
- Nicholas C. Price, Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third izd.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley-Interscience. ISBN 0471205036.
- Branden C, Tooze J.. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN: 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 izd.). Wiley Classics Library. ISBN 0471303097.
- Robert A. Copeland (2013). Evaluation of Enzyme Inhibitors in Drug Discovery: A Guide for Medicinal Chemists and Pharmacologists (2nd izd.). Wiley-Interscience. ISBN 111848813X.
- Gerhard Michal, Dietmar Schomburg (2012). Biochemical Pathways: An Atlas of Biochemistry and Molecular Biology (2nd izd.). Wiley. ISBN 0470146842.