IRNK guanililtransferaza
(Preusmjereno sa stranice IRNK završavajući enzim)
| IRNK guanililtransferaza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 2.7.7.50 | ||||||||
| CAS broj | 56941-23-2 | ||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB | RCSB PDB PDBe PDBj PDBsum | ||||||||
| |||||||||
IRNK guanililtransferaza (EC 2.7.7.50, iRNK završavajući enzim, informaciona RNK guanililtransferaza, protein lambda 2) je enzim sa sistematskim imenom GTP:iRNK guanililtransferaza.[1][2][3][4][5] Ovaj enzim katalizuje sledeću hemijsku reakciju
- GTP + (5')ppPur-iRNK difosfat + G(5')pppPur-iRNK
Ovaj enzim takođe može da modifikuje sintetički poli(A) i poli(G) čime formira strukture m7G(5')pppAn i m7G(5')pppGn.
- ↑ Ensinger, M.J., Martin, S.A., Paoletti, E. and Moss, B. (1975). „Modification of the 5′-terminus of mRNA by soluble guanylyl and methyl transferases from vaccinia virus”. Proc. Natl. Acad. Sci. USA 72: 2525-2529. PMID 1058472.
- ↑ Groner, Y., Gilbao, E. and Aviv, H. (1978). „Methylation and capping of RNA polymerase II primary transcripts by HeLa nuclear homogenates”. Biochemistry 17: 977-982. PMID 629955.
- ↑ Itoh, N., Yamada, H., Kaziro, Y. and Mizumoto, K. (1987). „Messenger RNA guanylyltransferase from Saccharomyces cerevisiae. Large scale purification, subunit functions, and subcellular localization”. J. Biol. Chem. 262: 1989-1995. PMID 3029058.
- ↑ Martin, S.A. and Moss, B. (1975). „Modification of RNA by mRNA guanylyltransferase and mRNA (guanine-7)methyltransferase from vaccinia virions”. J. Biol. Chem. 250: 9330-9335. PMID 1194287.
- ↑ Martin, S.A., Paoletti, E. and Moss, B. (1975). „Purification of mRNA guanylyltransferase and mRNA (guanine-7-) methyltransferase from vaccinia virions”. J. Biol. Chem. 250: 9322-9329. PMID 1194286.
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