Tingnan ang wikitext ng Cannabidiol

{{Drugbox
| Verifiedfields = changed
| Watchedfields = changed
| verifiedrevid = 457636058
| IUPAC_name = <nowiki>2-[(1</nowiki>''R'',6''R''<nowiki>)-6-isopropenyl-3-methylcyclohex-2-en-1-yl]-5-pentylbenzene-1,3-diol</nowiki>
| image = Cannabidiol Structural formula V1.svg
| image2 = CBD-3D-balls.png
<!--Clinical data-->
| tradename = Epidiolex
| Drugs.com = {{drugs.com|international|cannabidiol}}
| legal_US = Schedule I
| legal_US_comment = <ref>DEA News Release, DEA Eases Requirements for FDA Approved Clinical Trials on Cannabidiol (December 23, 2015) ("CBD is a Schedule I controlled substance as defined under the CSA."), http://www.dea.gov/divisions/hq/2015/hq122315.shtml {{Webarchive|url=https://web.archive.org/web/20170117183647/http://www.dea.gov/divisions/hq/2015/hq122315.shtml |date=2017-01-17 }}; Joseph T. Rannazzisi Deputy Assistant Administrator Drug Enforcement Administration Before the Caucus on International Narcotics Control, United States Senate, at 2 (June 24, 2015) (CBD is a Schedule I drug.); see also Frank Robison, Elvira Strehle-Henson, Cannabis Laws and Research at Colorado Institutions of Higher Education, COLO. LAW., OCTOBER 2015, AT 73, 76 ("[T]the DEA's position on CBD is clear—it is a Schedule I substance.").</ref>
| legal_CA = Schedule II
| legal_UK = POM
| legal_UK_comment = o Suplementong Pangkalusugan
| legal_AU = S4
<!--Pharmacokinetic data-->
| bioavailability = 13–19% (pambibig),<ref name = Mechoulam2002>{{cite journal |vauthors=Mechoulam R, Parker LA, Gallily R |title=Cannabidiol: an overview of some pharmacological aspects |journal=J Clin Pharmacol |volume=42 |issue=11 Suppl |pages=11S–19S |date=November 2002 |pmid=12412831 |type=Review|doi=10.1177/0091270002238789}}</ref> 11–45% (turan 31%; langhap)<ref name=Scuderi2009>{{cite journal |vauthors=Scuderi C, Filippis DD, Iuvone T, Blasio A, Steardo A, Esposito G |title=Cannabidiol in medicine: a review of its therapeutic potential in CNS disorders |journal=Phytother Res |volume=23 |issue=5 |pages=597–602 |date=May 2009|pmid=18844286 |doi=10.1002/ptr.2625 |type=Review}}</ref>

| elimination_half-life = 9 na oras<ref name = Mechoulam2002/>
<!--Identifiers-->
| IUPHAR_ligand = 4150
| CAS_number_Ref = {{cascite|correct|??}}
| CAS_number = 13956-29-1
| ATC_prefix = Wala
| ATC_suffix =
| PubChem = 644019
| ChEBI_Ref = {{ebicite|changed|EBI}}
| ChEBI = 69478
| DrugBank_Ref = {{drugbankcite|correct|drugbank}}
| DrugBank =
| ChemSpiderID_Ref = {{chemspidercite|correct|chemspider}}
| ChemSpiderID = 24593618
| UNII_Ref = {{fdacite|correct|FDA}}
| UNII = 19GBJ60SN5
<!--Chemical data-->
| C=21 | H=30 | O=2
| molecular_weight = 314.4636
| smiles = Oc1c(c(O)cc(c1)CCCCC)[C@@H]2\C=C(/CC[C@H]2\C(=C)C)C
| StdInChI_Ref = {{stdinchicite|correct|chemspider}}
| StdInChI = 1S/C21H30O2/c1-5-6-7-8-16-12-19(22)21(20(23)13-16)18-11-15(4)9-10-17(18)14(2)3/h9,12-13,17-18,22-23H,2,5-8,10-11H2,1,3-4H3/t17-,18+/m0/s1
| StdInChIKey_Ref = {{stdinchicite|correct|chemspider}}
| StdInChIKey = ZTGXAWYVTLUPDT-ZWKOTPCHSA-N
| melting_point = 66
| boiling_point = 180
| boiling_notes = <br />(hangganan: 160–180 °C)<ref>{{MEDRS|date=January 2014}} {{cite journal |vauthors=McPartland JM, Russo EB |year=2001 |title=Cannabis and cannabis extracts: greater than the sum of their parts? |journal=Journal of Cannabis Therapeutics |volume=1 |issue=3/4 |pages=103–132 |doi=10.1300/J175v01n03_08 |url=http://www.cannabis-med.org/data/pdf/2001-03-04-7.pdf |access-date=2013-09-29 |archive-date=2017-06-22 |archive-url=https://web.archive.org/web/20170622203721/http://www.cannabis-med.org/data/pdf/2001-03-04-7.pdf |url-status=dead }}</ref>
}}
Ang '''Cannabidiol''' ('''CBD''') ang isa sa mga 85 [[cannabinoid]] na matatagpuan sa halamang [[cannabis]] o [[marijuana]].<ref>{{Cite journal |author=El-Alfy, Abir T, et al. |title=Antidepressant-like effect of delta-9-tetrahydrocannabinol and other cannabinoids isolated from Cannabis sativa L. |journal=Pharmacology Biochemistry and Behavior |year=2010 |month=Jun |volume=95 |issue=4 |pages=434–42 |doi=10.1016/j.pbb.2010.03.004 |pmid=20332000 |pmc=2866040}}</ref> Ito ang pangunahing sangkap ng halaman na ikalawa sa [[THC]] at kumakatawan sa hanggang 40% nito.<ref name="Grlic_1962">{{cite journal
| last = Grlić
| first = Ljubiša
| authorlink = <!--Ljubiša Grlić-->
| author2 =
| title =A comparative study on some chemical and biological characteristics of various samples of cannabis resin
| journal =[[Bulletin on Narcotics]]
| volume =
| issue = 3
| pages =37–46
| publisher =[[United Nations Office on Drugs and Crime|UNODC]]
| year = 1962
| url =http://www.unodc.org/unodc/en/data-and-analysis/bulletin/bulletin_1962-01-01_3_page005.html
| doi =
| id =
| accessdate =  }}</ref> Kumpara sa THC, ang cannabidiol ay mas kaunting sikoaktibo at itinuturing na may mas malawak na sakop ng mga paggamot medikal kesa sa THC <ref name="Ashton, C.H. 2005">Ashton, C.H., Moore, P. B., Gallagher, P., Young, A. H. (2005). Cannabinoids in bipolar affective disorder: a review and discussion of their therapeutic potential. ''Journal of Psychopharmacology'' (U.K).</ref> kabilang sa epilepsy,<ref>{{cite pmid|22520455|noedit}}</ref> multiple sclerosis spasms,<ref>{{cite pmid|21449980|noedit}}</ref> anxiety disorders, bipolar Disorder,<ref name="Ashton, C.H. 2005"/> [[schizophrenia]],<ref name="Zuardi-2006">{{cite journal
| last = Zuardi
| first = A.W
| author2 = J.A.S. Crippa, J.E.C. Hallak, F.A. Moreira, F.S. Guimarães
| year = 2006
| title = Cannabidiol, a ''Cannabis sativa'' constituent, as an antipsychotic drug
| journal = [[Brazilian Journal of Medical and Biological Research|Braz. J. Med. Biol. Res.]]
| volume = 39
| issue = 4
| pages = 421–429
| url = http://www.scielo.br/pdf/bjmbr/v39n4/6164.pdf
| format = PDF
| pmid = 16612464
| doi = 10.1590/S0100-879X2006000400001
}}</ref>  nausea, kombulsiyon at pamamaga gayundin sa pagpigil ng paglago ng selulang [[kanser]].<ref name="recentadvances">{{cite journal
| last = Mechoulam
| first = R.
| authorlink = 
| author2 = M. Peters, Murillo-Rodriguez
| title = Cannabidiol - recent advances
| journal = Chemistry & Biodiversity
| volume = 4
| issue = 8
| pages = 1678–1692
| publisher = 
| date = 21 Aug 2007
| url = http://www3.interscience.wiley.com/journal/115806131/abstract
| pmid = 17712814
| doi = 10.1002/cbdv.200790147
}}{{Dead link|date=August 2021 |bot=InternetArchiveBot |fix-attempted=yes }}</ref> Ang Cannabidiol ay nagpakita ng mga epektong sedatibo, pampakalma sa mga pagsubok sa hayop<ref name="pmid6269680">aPawesomeLife, "[https://apawesomelife.com/best-cbd-oil-for-dogs-with-arthritis-6b16895d5f3b Will CBD oil help my dog’s arthritis and joint pain?]{{Dead link|date=Mayo 2022 |bot=InternetArchiveBot |fix-attempted=yes }}" thru studies extracted from [https://www.akcchf.org/research/research-portfolio/2323.html AKC Canine Health Foundation] (2017), [https://www.prnewswire.com/news-releases/cornell-university-college-of-veterinary-medicine-presents-first-pharmacokinetics-study-on-cannabinoids-for-dogs-300592667.html Cornell University College of Veterinary Medicine] (2018), and [https://www.akcchf.org/research/research-portfolio/2323.html American Veterinary Medical Association] (2021)</ref> o kaginhawan ng artritis sa aso.<ref name="pmid6269680" /> Ang ibang pagsasaliksik ay nagpapakita na ito ay nagpapataas ng  pagiging alerto.<ref>{{cite journal
| last = Nicholson
| first = AN
| authorlink =
| author2 = C Turner, BM Stone, and PJ Robson
| year = 2004
| month = June
| title = Effect of Delta-9-tetrahydrocannabinol and cannabidiol on nocturnal sleep and early-morning behavior in young adults
| journal = [[J Clin Psychopharmacol]]
| volume = 24
| issue = 3
| pages = 305–13
| issn = 0271-0749
| pmid = 15118485
| url = http://safeaccess.ca/research/pdf/Nicholson_CBME_Sleep.pdf
| doi = 10.1097/01.jcp.0000125688.05091.8f }}</ref> Ang Cannabidiol ay naipakitang nagbawas ng paglago ng mga selulang [[kanser sa suso]] [[in vitro]] at nagbawas ng kanilang pagsalakay.<ref name="pmid18025276">{{cite journal
| author=McAllister SD, Christian RT, Horowitz MP, Garcia A, Desprez PY
| title=Cannabidiol as a novel inhibitor of Id-1 gene expression in aggressive breast cancer cells
| journal=Mol. Cancer Ther.
| volume=6
| issue=11
| pages=2921–7
| year=2007
| pmid=18025276
| doi=10.1158/1535-7163.MCT-07-0371
}}</ref>
==Mga sanggunian==
{{reflist}}

[[Kategorya:Mga cannabinoid]]
[[Kategorya:Mga kompuwestong kimikal]]