This paper proposes an on-chip loop gain variation compensation architecture for a clock and data recovery (CDR) LSI. The CDR LSI using the proposed architecture can meet the jitter specifications recommended in ITU-T G. 958 under wide variation of temperature and supply voltage. The relation between the jitter specifications and the loop gain is derived theoretically. Gain-variation characteristics of component circuits are studied by circuit simulation. The proposed architecture uses voltage controllers to reduce the gain variation of the LC voltage controlled oscillator (LC-VCO) circuit and charge-pump circuit. The voltage controllers are designed to have a first-order positive coefficient to temperature, which is found by an analysis of the gain variation characteristics. An STM-16 CDR with the proposed architecture is implemented in 0.20-μm fully depleted CMOS/SOI. The CDR shows a wide capture range of ±140MHz and meets both the jitter transfer and the jitter tolerance specifications in the ambient temperature range from -40 to 85°C and with the supply voltage variation of ±6%.