Researchers from the Indian Institute of Technology-Madras have shown that the active compound from the common household spice turmeric — curcumin — can enhance cancer cell death.
About:
TNF-related apoptosis-inducing ligand (TRAIL) is an agent with the ability to programme cell death (apoptosis) and has triggered many preclinical studies the world over.
The IIT-M research team chose curcumin as it is known to inhibit carcinogenesis and induce apoptosis in various cancer cells.
The researchers isolated leukaemia cells from cancer patients and found that non-toxic concentrations of curcumin can significantly increase the efficiency of TRAIL-induced cell death.
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