Hrs regulates endosome membrane invagination and tyrosine kinase receptor signaling in Drosophila (Q43879100)

27 November 2017

title

Hrs regulates endosome membrane invagination and tyrosine kinase receptor signaling in Drosophila (English)

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Hepatocyte growth factor regulated tyrosine kinase substrate Dmel_CG2903

27 November 2017

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GOA release 2020-03-11

author

Hugo J. Bellen

6

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27 November 2017

Thomas E Lloyd

1

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27 November 2017

Richard Atkinson

2

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27 November 2017

Mark N Wu

3

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27 November 2017

Yi Zhou

4

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27 November 2017

Giuseppa Pennetta

5

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27 November 2017

language of work or name

English

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publication date

1 January 2002

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27 November 2017

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27 November 2017

volume

108

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27 November 2017

issue

2

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27 November 2017

page(s)

261-269

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Hrs is associated with STAM, a signal-transducing adaptor molecule. Its suppressive effect on cytokine-induced cell growth

27 November 2017

cites work

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Hrs-2 is an ATPase implicated in calcium-regulated secretion

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Hrs-2 regulates receptor-mediated endocytosis via interactions with Eps15

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Regulation of synapse structure and function by the Drosophila tumor suppressor gene dlg

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Phosphatidylinositol(3)-phosphate signaling mediated by specific binding to RING FYVE domains

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Regulation of signal transduction by endocytosis

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7 January 2021

Hrs interacts with sorting nexin 1 and regulates degradation of epidermal growth factor receptor

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7 January 2021

Synaptic transmission persists in synaptotagmin mutants of Drosophila

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7 January 2021

Torso, a receptor tyrosine kinase required for embryonic pattern formation, shares substrates with the sevenless and EGF-R pathways in Drosophila

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Kinase activity controls the sorting of the epidermal growth factor receptor within the multivesicular body

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7 January 2021

Multivesicular endosomes containing internalized EGF-EGF receptor complexes mature and then fuse directly with lysosomes

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7 January 2021

Quantitative variations in the level of MAPK activity control patterning of the embryonic termini in Drosophila.

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A new ticket for entry into budding vesicles-ubiquitin

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A ubiquitin-interacting motif conserved in components of the proteasomal and lysosomal protein degradation systems

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7 January 2021

Separate endocytic pathways of kinase-defective and -active EGF receptor mutants expressed in same cells

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7 January 2021

Transformational process of the endosomal compartment in nephrocytes of Drosophila melanogaster

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7 January 2021

Growth factor-induced tyrosine phosphorylation of Hrs, a novel 115-kilodalton protein with a structurally conserved putative zinc finger domain

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7 January 2021

Hrs and hbp: possible regulators of endocytosis and exocytosis

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7 January 2021

Hrs, a FYVE finger protein localized to early endosomes, is implicated in vesicular traffic and required for ventral folding morphogenesis

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7 January 2021

Hrs, a Tyrosine Kinase Substrate with a Conserved Double Zinc Finger Domain, Is Localized to the Cytoplasmic Surface of Early Endosomes

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7 January 2021

Reversible blockage of membrane retrieval and endocytosis in the garland cell of the temperature-sensitive mutant of Drosophila melanogaster, shibirets1.

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Several levels of EGF receptor signaling during photoreceptor specification in wild-type, Ellipse, and null mutant Drosophila

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7 January 2021

VHS domain marks a group of proteins involved in endocytosis and vesicular trafficking

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7 January 2021

Crystal structure of the VHS and FYVE tandem domains of Hrs, a protein involved in membrane trafficking and signal transduction

1 reference

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7 January 2021

Hgs (Hrs), a FYVE domain protein, is involved in Smad signaling through cooperation with SARA.

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7 January 2021

Membrane pinch-off and reinsertion observed in living cells of Drosophila

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7 January 2021

Fab1p PtdIns(3)P 5-kinase function essential for protein sorting in the multivesicular body

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7 January 2021

The torso receptor protein-tyrosine kinase signaling pathway: an endless story

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7 January 2021

VPS27 controls vacuolar and endocytic traffic through a prevacuolar compartment in Saccharomyces cerevisiae

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7 January 2021

Hrs recruits clathrin to early endosomes

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7 January 2021

Establishment of ventral cell fates in the Drosophila embryonic ectoderm requires DER, the EGF receptor homolog.

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7 January 2021

A thousand and one roles for the Drosophila EGF receptor

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7 January 2021

Secreted Spitz triggers the DER signaling pathway and is a limiting component in embryonic ventral ectoderm determination.

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7 January 2021

Receptor signalling and the regulation of endocytic membrane transport

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7 January 2021

EEA1 links PI(3)K function to Rab5 regulation of endosome fusion

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7 January 2021

Coiled coils in both intracellular vesicle and viral membrane fusion

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7 January 2021

Torso receptor activity is regulated by a diffusible ligand produced at the extracellular terminal regions of the Drosophila egg

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7 January 2021

Improved stability of Drosophila larval neuromuscular preparations in haemolymph-like physiological solutions

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7 January 2021

Endosomal localization and receptor dynamics determine tyrosine phosphorylation of hepatocyte growth factor-regulated tyrosine kinase substrate

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7 January 2021

Enhancement of tyrosine kinase activity of the Drosophila epidermal growth factor receptor homolog by alterations of the transmembrane domain

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7 January 2021

ROP, the Drosophila Sec1 homolog, interacts with syntaxin and regulates neurotransmitter release in a dosage-dependent manner.

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7 January 2021

Syntaxin 1A interacts with multiple exocytic proteins to regulate neurotransmitter release in vivo.

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7 January 2021

Phosphoinositide 3-kinases and their FYVE domain-containing effectors as regulators of vacuolar/lysosomal membrane trafficking pathways

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7 January 2021

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Identifiers

DOI

1 reference

27 November 2017

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