Interferon alfa-2b
| Clinical data | |
|---|---|
| MedlinePlus | a690006 |
| License data | |
| Routes of administration | Subcutaneous, intramuscular |
| ATC code | |
| Legal status | |
| Legal status | |
| Identifiers | |
| IUPHAR/BPS | |
| DrugBank | |
| ChemSpider |
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| ChEMBL | |
| ECHA InfoCard | 100.208.165 |
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Interferon alfa-2b is an antiviral or antineoplasic drug, that was originally discovered in the laboratory of Charles Weissmann at the University of Zurich. It was developed at Biogen, and ultimately marketed by Schering-Plough under the tradename Intron-A. It has been used for a wide range of indications, including viral infections and cancers.
This drug is approved around the world for the treatment of chronic hepatitis C, chronic hepatitis B, hairy cell leukemia, Behçet's disease, chronic myelogenous leukemia, multiple myeloma, follicular lymphoma, carcinoid tumor, mastocytosis and malignant melanoma.
| Interferon alfa-2b products[1] | |||
|---|---|---|---|
| Product | Manufacturer | Features | Special uses |
| Alpharona | Pharmaclon | ||
| Intron-A/IntronA | Schering-Plough | ||
| Realderon | Teva | ||
| Reaferon EC | GNC Vector | ||
| Reaferon EC-Lipint | Vector-Medica | liposomal | |
| Infagel | Vector-Medica | ointment | |
| Recolin | Vector-Medica | ||
| Altevir | Bioprocess subsidiary | liquid, free of HSA | |
| Kipferon | Alfarm | combination with IgM, IgA, IgG | |
| Giaferon | A/S Vitafarma | ||
| Genferon | Biocad | ||
| Opthalamoferon | Firn-M | with dimedrol | eye infections |
See also
References
- ^ Dmitrij I. Bairamashvili1 and Mikhail L. Rabinovich2* (2007). "Russia through the prism of the world biopharmaceutical market" (PDF). Biotechnol. J. 2. Archived from the original (PDF) on 2012-02-24. Retrieved 2009-06-14.
{{cite journal}}: CS1 maint: numeric names: authors list (link)
External links
- Intron-A Summary of Product Characteristics
- Nagata S, Taira H, Hall A, et al. (Mar 1980). "Synthesis in E. coli of a polypeptide with human leukocyte interferon activity". Nature. 284 (5754): 316–20. doi:10.1038/284316a0. PMID 6987533.
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