Cromolyn sodium
Cromolyn sodium is a stabilizer of mast cell membrane [1].
Cromolyn sodium has been used to treat for asthma for many years. It is a derivative of khellin and is proved to be a unique antiallergic agent. The prior administration of cromolyn sodium inhibits allergen-induced histamine release in the animal experiments. Because the oral absorption of cromolyn sodium is minimal and only the powder form of it is available, cromolyn sodium is usually used through being inhaled from a special apparatus. Cromolyn sodium can suppress both immediate and late-onset asthmatic responses and suppress the release of NCF-A. It also inhibits the impairment of mucociliary transport induced by specific bronchial challenge. Moreover, cromolyn sodium also ameliorates exercise-induced asthma [1].
References:
[1] Bernstein I L. Cromolyn sodium. CHEST Journal, 1985, 87(1_Supplement): 68S-73S.
| Physical Appearance | A solid |
| Storage | Desiccate at -20°C |
| M.Wt | 512.33 |
| Cas No. | 15826-37-6 |
| Formula | C23H14Na2O11 |
| Solubility | insoluble in EtOH; ≥15.07 mg/mL in H2O; ≥5.12 mg/mL in DMSO |
| Chemical Name | disodium;5-[3-(2-carboxylato-4-oxochromen-5-yl)oxy-2-hydroxypropoxy]-4-oxochromene-2-carboxylate |
| SDF | Download SDF |
| Canonical SMILES | C1=CC2=C(C(=C1)OCC(COC3=CC=CC4=C3C(=O)C=C(O4)C(=O)[O-])O)C(=O)C=C(O2)C(=O)[O-].[Na+].[Na+] |
| Shipping Condition | Small Molecules with Blue Ice, Modified Nucleotides with Dry Ice. |
| General tips | We do not recommend long-term storage for the solution, please use it up soon. |
Quality Control & MSDS
- View current batch:
Chemical structure
