kb NB 142-70
Catalog No.
A3524
Inhibitor of protein kinase D,selective
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kb NB 142-70 is a selective protein kinase D (PKD) inhibitor (IC50 values are 28.3, 58.7 and 53.2 nM for PKD1, 2 and 3 respectively). Kb NB 142-70 inhibits prostate cancer cell migration and invasion and reduces wound healing in vitro. Kb NB 142-70 displays prominent cytotoxic and anti-proliferative effects.
| Physical Appearance | A solid |
| Storage | Store at -20°C |
| M.Wt | 251.32 |
| Cas No. | 1233533-04-4 |
| Formula | C11H9NO2S2 |
| Solubility | insoluble in H2O; ≥12.9 mg/mL in DMSO; ≥8.05 mg/mL in EtOH with gentle warming and ultrasonic |
| Chemical Name | 9-hydroxy-3,4-dihydro-2H-[1]benzothiolo[2,3-f][1,4]thiazepin-5-one |
| SDF | Download SDF |
| Canonical SMILES | C1CSC2=C(C(=O)N1)SC3=C2C=C(C=C3)O |
| Shipping Condition | Small Molecules with Blue Ice, Modified Nucleotides with Dry Ice. |
| General tips | We do not recommend long-term storage for the solution, please use it up soon. |
Quality Control & MSDS
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Chemical structure
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