(1)What is epigenetics? What is the role of methylation in epigenetics? At what level (Replication, Transcription, Translation) does epigenetics act? (2) What is the effect of splicing on RNA? What is the purpose of alternate splicing? (3) If a DNA sequence is 5' TCC GGT CAT 3' what are the RNA and protein sequences that can be made from the strand? Use this codon table บบบา UUC UUA UUG CUU CUC CUA CUG a} Phe GUU GUC GUA GUG. Leu Leu AUU AUC AUA AUG Met lle Val UCU UCC UCA UCG CCU CCC CCA CCG ACU ACC ACA ACG GCU GCC GCA GCG Ser Pro Thr Ala UAU Tyr UAC UAA UAG CAU č} CAC CAA CAG AAU AAC AAA AAG GAU GAC GAG} Stop His Gln Asn Lys Asp Glu UGU UGC Cys UGA Stop UGG Trp CGU CGC CGA CGG. Arg AGU AGC AGA } Arg AGG GGU GGC GGA GGG Ser Gly 4. Normal yeast cells can survive on a diet of sugars, a few simple salts and one vitamin. They can make all of their amino acids and other vitamins using what can be found in their diet. You identify a mutant strain that can only survive if given alanine, which is one of the amino acids. The mutation is recessive. Based on this information, what would you predict that the normal function of the dominant allele is?

What is the function of RAG1? What will happen if RAG1's function is lost due to mutations?

What are the Results of tra splicing when Sxl protein is present?

In the early 1960's scientists knew the structure of DNA, however they didn't know how it coded for the expression of proteins. To find out, American Biochemist, Marshall Nirenberg did an experiment and figured out the first codon! To begin he made a solution of Uracil (U), and linked the nucleotides together to form a synthetic RNA molecule which read-UUUUUUU... etc. Therefore, no matter where the message started or stopped, the codon triplets always read UUU, UUU, UUU. Next, he added the poly-U chain to a solution of ribosomes and other ingredients needed for polypeptide synthesis. The result was a polypeptide containing the amino acid phenylalanine. Thus, Niernberg learned that the RNA codon UUU specifies the amino acid phenylalanine. What is the central theme of molecular genetics? Now let's look at the entire process of taking DNA and creating Proteins from that code: Say we have the following nucleotide chain in DNA: T-A-C-T-A-G-C-G-G-A-T-A-G-C-A-T-C-C-C-G-G-G-A-T-A-T-T DNA What…