Protein methylation has been most studied in histones, where the transfer of methyl groups from S-adenosyl methionine is catalyzed by histone methyltransferases. Histones that are methylated on ...
Methylation is one of the more prevalent ... experimental animal model system they could use to study the role of histone proteins in regulating genes. For this study, researchers examined ...
LMU molecular biologist Gunnar Schotta decodes the epigenetic silencing of problematic retroviral gene sequences.
These attendant proteins bind to histones and nucleosomal ... studies to determine that acetylation of histone H3 and methylation at lysine residue K4 appeared to coincide with each other.
Caltech researchers have developed a new method to map the positions of hundreds of DNA-associated proteins within cell ...
A cell protein previously believed only to provide a scaffolding for DNA has also been shown to directly influence DNA ...
Epigenetic modifications, such as DNA methylation and histone modifications, can affect gene expression by altering the accessibility of DNA to transcription factors and other regulatory proteins. DNA ...
Alterations in methylation patterns could potentially ... do not possess histones like eukaryotic cells, they have ...
and on post-translation histone and DNA modifications impacting on epigenetic regulation. Additional areas include RNA-mediated events ranging from cofactor recognition by riboswitches, catalysis by ...