Originally derived from camelid heavy chain antibodies, single domain or VHH antibodies can bind epitopes that are inaccessible to conventional monoclonal antibodies due to their small size. Because ...

The Harbour Mice ® platform generates fully human monoclonal antibodies in both the two heavy and two light chains (H2L2) format and the heavy chain-only (HCAb) format, eliminating the need for ...

The method for creating bispecific κλ bodies is simple: a production cell expresses a single heavy chain, alongside κ and λ light chains, which self-assemble into functional antibodies.

To do this, scientists typically integrate the genes encoding the relevant antibody’s subunits, called the heavy and light chain ... At present, that’s the only way to harvest enough of ...

“Immunoglobin” is the term for a group of proteins that work as antibodies and consist of four protein chains. Two of these chains are light chains, and two are heavy chains. In AL ...

The Harbour Mice ® platform generates fully human monoclonal antibodies in both the two heavy and two light chains (H2L2) format and the heavy chain-only (HCAb) format, eliminating the need for ...