suggesting influences beyond traditional purine metabolism pathways." This discovery is crucial, as it points to an impairment in the ATP recycling system. ATP is essential for cellular energy use ...

Purine metabolism and signaling pathways are potential targets for therapeutic interventions in various diseases, such as cancer, autoimmune disorders, and infectious diseases. Purine analogues, such ...

The following is a summary of “Current status of serum metabolites biomarkers for polyps and colorectal cancer: a systematic ...

Hitchings hypothesized that by preventing those purines from entering the metabolic pathway that leads to DNA synthesis, they could stop the production of DNA and thereby stop cell growth. Along the ...