where opioids are known to inhibit neurotransmitter release from dorsal root ganglion projections in the dorsal horn of the spinal cord (MacDonald and Nelson 1978; Mudge et al. 1979; Yaksh 1993).

The FDA is set to consider approval of an alternative to opioids developed by Vertex Pharmaceuticals, The Washington Post reported Jan. 13.

“This suggests that endocannabinoids and opioids may not act together in areas of the brain and spinal cord involved in analgesia,” Dr. Rajadhyaksha said. “In contrast, their interaction in ...

Vertex Pharma could be close to succeeding in the long-standing quest to find an alternative to potentially addictive opioids for the ... pain signals to the spinal cord from peripheral nerves.

They block pain signals in the brain, binding to opioid receptors in the brain, spinal cord, and elsewhere. “Basically, it’s, as the name suggests, a synthetic drug made in the laboratory.

This means treatments are designed to target various pain receptors beyond opioid receptors in the spinal cord. Multimodal analgesia uses a combination of at least two medications or anesthetic ...

They block pain signals in the brain, binding to opioid receptors in the brain, spinal cord, and elsewhere. “Basically, it’s, as the name suggests, a synthetic drug made in the laboratory.

By Andy Furman NKyTribune reporter It was a win – for Kentucky. And a big one. The Attorney General of the Commonwealth, R-Ky ...

Here’s a look at the opioid crisis. Experts say the United States is in the throes of an opioid epidemic. An estimated 8.9 million Americans aged 12 and older misused opioids in 2023. Opioids are ...