Deoxyuridine (dU) is a compound and a nucleoside. It belongs to a class of compounds known as Pyrimidine 2'-deoxyribonucleosides [1] and closely resembles the chemical composition of uridine but without the presence of the 2' hydroxyl group. Idoxuridine and Trifluridine are variants of deoxyuridine used as antiviral drugs.

Deoxyuridine | C9H12N2O5 | CID 13712 - structure, chemical names, physical and chemical properties, classification, patents, literature, biological activities, safety/hazards/toxicity information, supplier lists, and more.

May 21, 2018 · Uracil in DNA can be generated by cytosine deamination or dUMP misincorporation; however, its distribution in the human genome is poorly understood. Here we present a selective labeling and...

Deoxythymidine is an intermediate in the degradation of thymine deoxynucleotides and of deoxyribonucleic acid (DNA). In most organisms, deoxythymidine is of minor importance for the biosynthesis of thymine deoxynucleotides and, therefore, for DNA synthesis.

Idoxuridine (5-iodo-29-deoxyuridine), a thymidine analogue synthesized in 1959, was the first FDA-approved antiviral medication. 44 Topical idoxuridine 5–15% in dimethyl sulfoxide is ineffective for genital HSV, 45 and has limited efficacy in both VZV and HSV labialis when applied every 4 hours for 4 days. 46,47 Currently, idoxuridine is only ...

Recently, a novel method for detecting DNA synthesis has been developed by using 5-ethynyl-2′-deoxyuridine (EdU) (Buck et al., 2008; Cappella et al., 2008; Chehrehasa et al., 2009; Salic and Mitchison, 2008). EdU, also a thymidine analogue, is incorporated into …

The synthetic halogenated pyrimidine analog, 5-bromo-2′-deoxyuridine (BrdU), is a marker of DNA synthesis. This exogenous nucleoside has generated important insights into the cellular mechanisms of the central nervous system development in a variety of animals including insects, birds, and mammals.

Jun 13, 2005 · 2'-Deoxyuridine. An antimetabolite that is converted to deoxyuridine triphosphate during DNA synthesis. Laboratory suppression of deoxyuridine is used to diagnose megaloblastic anemias due to vitamin B12 and folate deficiencies.

Deoxyuridine is a chemical compound that is also known by various trade names such as Idoxuridine, Stoxil, and others. You might find these chapters and articles relevant to this topic. Eric Scholar, in xPharm: The Comprehensive Pharmacology Reference, 2007.

Jan 31, 2019 · BT549 cells were transfected with siRNA targeting Lig4 or NT as described. Cells were pulsed with the thymidine analog 5-iodo-2′-deoxyuridine (IdU; 20 μM) in complete growth medium and incubated for 15 min at 37°C.