H1 antagonist - Wikipedia
H1 antagonists, also called H1 blockers, are a class of medications that block the action of histamine at the H 1 receptor, helping to relieve allergic reactions.
First-Generation vs. Second-Generation Antihistamines: What’s …
Dec 12, 2024 · Typically, antihistamines that treat H-2 receptor antagonists treat gastrointestinal symptoms. Both first-generation and minimally sedating antihistamines treat H-1 receptor antagonists.
Antihistamine Types & Side Effects - Cleveland Clinic
So, H1 receptor antihistamines mainly treat allergy symptoms. The U.S. Food and Drug Administration (FDA) has approved the use of H1 antihistamines to help treat the following conditions: Allergic rhinitis (hay fever). Allergic conjunctivitis (pink eye).
List of Common Antihistamines + Uses & Side Effects - Drugs.com
Apr 17, 2023 · Antihistamines block histamine release from histamine-1 receptors and are mostly used to treat allergies or cold and flu symptoms, although some first-generation antihistamines (also called sedating antihistamines) may be used for …
H1 antihistamines: classification, action, uses, side effects
H1 antihistamines compete with histamine to block its effects at H1 receptors, such as cetirizine, promethazine, pheniramine, azelastine etc. They have antiallergic actions while have poor antipruritic, antiemetic and antitussive actions.
H1 Antihistamines: Current Status and Future Directions - PMC
In this review, we compare and contrast the clinical pharmacology, efficacy, and safety of first-generation H 1 antihistamines and second-generation H 1 antihistamines. First-generation H 1 antihistamines cross the blood-brain barrier, and in usual doses, they potentially cause sedation and impair cognitive function and psychomotor performance.
Histamine H1 Antagonists - DrugBank Online
A H1 receptor antihistamine used in the treatment of seasonal allergies, and various allergic reactions including sneezing, runny nose, itchy/watery eyes, itching of nose or throat, pruritus, urticaria, insect bites/stings, and allergic rashes.
Antihistamines - StatPearls - NCBI Bookshelf
Jul 10, 2023 · Antihistamines are a pharmaceutical class of drugs that act to treat histamine-mediated conditions. There are two main classes of histamine receptors: H-1 receptors and H-2 receptors. Antihistamine drugs that bind to H-1 receptors are generally used to …
H1-receptor Antihistamines. Two Generations: Review of Clinical …
Jan 31, 2022 · Antihistamines block the H1-receptors, preventing and stopping the effects of histamine. The blockade occurs by the mechanism of competitive inhibition, and the affinity of drugs for H1-receptors is much lower than that of histamine. Drugs do not displace histamine bound to the receptor, but only block free receptors.
Antihistamines: Uses, Types, and Side-Effects - Patient
Oct 11, 2022 · Antihistamines work by physically blocking the H1 receptors, stopping histamine from reaching its target. This decreases your body's reaction to allergens and therefore helps to reduce the troublesome symptoms associated with allergy.