Ventolin Hfa

— THERAPEUTIC CATEGORIES —
  • Asthma/COPD
PAGE CONTENTS
  • Jump to Section
  • Generic Name & Formulations
  • Indications
  • Dosage and Administration
  • Contraindications
  • Boxed Warnings
  • Warnings/Precautions
  • Pharmacokinetics
  • Interactions
  • Adverse Reactions
  • Clinical Trials
  • Note
  • Patient Counseling

    • Ventolin Hfa Generic Name & Formulations

    Legal Class

    Rx

    General Description

    Albuterol 90mcg/inh; metered-dose aerosol; contains hydrofluoroalkane; CFC-free.

    Pharmacological Class

    Beta-2 agonist.

    How Supplied

    Inhalation aerosol (w. dose counter)—8g (60 inh), 18g (200 inh)

    Manufacturer

    GlaxoSmithKline

    Generic Availability

    NO

    Mechanism of Action

    The pharmacological effects of beta2-adrenoceptor agonist drugs are at least in part attributable to stimulation of intracellular adenyl cyclase, the enzyme that catalyzes the conversion of adenosine triphosphate (ATP) to cyclic-3, 5-adenosine monophosphate (cyclic AMP). Increased cyclic AMP levels cause relaxation of bronchial smooth muscle.

    Ventolin Hfa Indications

    Indications

    Bronchospasm.

    Ventolin Hfa Dosage and Administration

    Adults and Children

    <4yrs: not established. ≥4yrs: 2 inh every 4–6hrs as needed; 1 inh every 4hrs may suffice. Exercise-induced bronchospasm: 2 inh 15–30mins before exercise.

    Administration

    Prime before using for the first time, when the inhaler has not been used for more than 2 weeks, or when the inhaler has been dropped. To prime, release 4 sprays into the air away from the face, shaking well before each spray.

    Nursing Considerations

    Prime before using for the first time, when the inhaler has not been used for more than 2 weeks, or when the inhaler has been dropped. To prime, release 4 sprays into the air away from the face, shaking well before each spray.

    Ventolin Hfa Contraindications

    Not Applicable

    Ventolin Hfa Boxed Warnings

    Not Applicable

    Ventolin Hfa Warnings/Precautions

    Warnings/Precautions

    Avoid excessive use. Sensitivity to sympathomimetics. Discontinue if paradoxical bronchospasm, immediate hypersensitivity reactions, or cardiovascular effects occur. Cardiovascular disease (eg, coronary insufficiency, arrhythmias, hypertension). Diabetes. Hyperthyroidism. Seizure disorders. Reevaluate periodically. Elderly. Labor & delivery. Pregnancy: monitor closely. Nursing mothers: not recommended.

    Ventolin Hfa Pharmacokinetics

    See Literature

    Ventolin Hfa Interactions

    Interactions

    Avoid MAOIs, tricyclics within 14 days (increased cardiovascular effects). Oral sympathomimetics: not recommended. Antagonized by β-blockers. Monitor digoxin. Caution with other drugs that may lower serum potassium (eg, diuretics).

    Ventolin Hfa Adverse Reactions

    Adverse Reactions

    Throat irritation, viral respiratory infections, upper respiratory inflammation, cough, musculoskeletal pain; hypokalemia, paradoxical bronchospasm, cardiovascular effects, hypersensitivity reactions (eg, rash, urticaria, angioedema).

    Ventolin Hfa Clinical Trials

    See Literature

    Ventolin Hfa Note

    Not Applicable

    Ventolin Hfa Patient Counseling

    See Literature

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