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Open Access Publications from the University of California

Scholarly Works (8 results)

  • Article
  • Peer Reviewed
UC Merced Previously Published Works (2021)
To address complex problems, scholars are increasingly faced with challenges of integrating diverse knowledge domains. We analyzed the evolution of this convergence paradigm in the broad ecosystem of brain science, which provides a real-time testbed for evaluating two modes of cross-domain integration - subject area exploration via expansive learning and cross-disciplinary collaboration among domain experts. We show that research involving both modes features a 16% citation premium relative to a mono-disciplinary baseline. Further comparison of research integrating neighboring versus distant research domains shows that the cross-disciplinary mode is essential for integrating across relatively large disciplinary distances. Yet we find research utilizing cross-domain subject area exploration alone - a convergence shortcut - to be growing in prevalence at roughly 3% per year, significantly faster than the alternative cross-disciplinary mode, despite being less effective at integrating domains and markedly less impactful. By measuring shifts in the prevalence and impact of different convergence modes in the 5-year intervals before and after 2013, our results indicate that these counterproductive patterns may relate to competitive pressures associated with global Human Brain flagship funding initiatives. Without additional policy guidance, such Grand Challenge flagships may unintentionally incentivize such convergence shortcuts, thereby undercutting the advantages of cross-disciplinary teams in tackling challenges calling on convergence.
    • Article
    • Peer Reviewed
    UC Merced Previously Published Works (2021)
    Abstract: To address complex problems, scholars are increasingly faced with challenges of integrating diverse domains. We analyzed the evolution of this convergence paradigm in the ecosystem of brain science, a research frontier that provides a contemporary testbed for evaluating two modes of cross-domain integration: (a) cross-disciplinary collaboration among experts from academic departments associated with disparate disciplines; and (b) cross-topic knowledge recombination across distinct subject areas. We show that research involving both modes features a 16% citation premium relative to a mono-domain baseline. We further show that the cross-disciplinary mode is essential for integrating across large epistemic distances. Yet we find research utilizing cross-topic exploration alone—a convergence shortcut—to be growing in prevalence at roughly 3% per year, significantly outpacing the more essential cross-disciplinary convergence mode. By measuring shifts in the prevalence and impact of different convergence modes in the 5-year intervals up to and after 2013, we find that shortcut patterns may relate to competitive pressures associated with Human Brain funding initiatives launched that year. Without policy adjustments, flagship funding programs may unintentionally incentivize suboptimal integration patterns, thereby undercutting convergence science’s potential in tackling grand challenges.
      • Article
      • Peer Reviewed
      Western Journal of Emergency Medicine: Integrating Emergency Care with Population Health, Volume 25, Issue 1 (2024)

      Introduction: People without reliable access to healthcare are more likely to be diagnosed with late-stage cancer that could have been treated more effectively if diagnosed earlier. Emergency departments (ED) may be a novel place for cancer screening education for underserved patients. In this study we sought to determine patient characteristics and barriers to cancer screening for those patients who presented to a large, academic safety-net ED and were overdue for breast, cervical, and colorectal cancer screening since the coronavirus 2019 (COVID-19) pandemic.

      Methods: Adult ED patients eligible for at least one cancer screening based on US Preventive Serivces Task Force guidelines completed a web-based survey. We examined the association of demographic characteristics and having a personal physician with being overdue on screening using chi-square or the Fisher exact test for categorical variables and t-tests for continuous variables.

      Results: Of 221 participants, 144 were eligible for colorectal, 96 for cervical, and 55 for breast cancer screening. Of eligible patients, 46% (25/55) were overdue for breast cancer screening, 43% (62/144) for colorectal, and 40% (38/96) for cervical cancer screening. There were no significant characteristics associated with breast cancer screening. Being overdue for cervical cancer screening was significantly more likely for patients who were of Asian race (P = 0.02), had less than a high school diploma (P = 0.01), and were without a routine checkup within the prior five years (P = 0.01). Overdue for colorectal cancer screening was associated with patients not having insurance (P = 0.04), being in their 40s (P = 0.03), being Hispanic (P = 0.01), and not having a primary care physician (P = 0.01). Of 97 patients overdue for at least one screening, the most common barriers were cost (37%), lack of time (37%), and lack of knowledge of screening recommendations (34%). Only 8.3% reported that the COVID-19 pandemic delayed their screening.

      Conclusion: The ED may be a novel setting to target patients for cancer screening education. Future work that refers patients to free screening programs and primary care physicians mayhelp improve disparities in cancer screening and cancer mortality rates for underserved populations.

        Cover page: Characteristics and Barriers of Emergency Department Patients Overdue for Cancer ScreeningCreative Commons 'BY' version 4.0 license
        • Article
        • Peer Reviewed
        UC Merced Previously Published Works (2019)
        The ability to objectively assess academic performance is critical to rewarding academic merit, charting academic policy, and promoting science. Quintessential to performing these functions is first the ability to collect valid and current data through increasingly automated online interfaces. Moreover, it is crucial to remove disciplinary and other biases from these data, presenting them in ways that support insightful analysis at various levels. Existing systems are lacking in some of these respects. Here we present Scholar Plot (SP), an interface that harvests bibliographic and research funding data from online sources. SP addresses systematic biases in the collected data through nominal and normalized metrics. Eventually, SP combines synergistically these metrics in a plot form for expert appraisal, and an iconic form for broader consumption. SP's plot and iconic forms are scalable, representing equally well individual scholars and their academic units, thus contributing to consistent ranking practices across the university organizational structure. In order to appreciate the design principles underlying SP, in particular the informativeness of nominal vs. normalized metrics, we also present the results of an evaluation survey taken by senior faculty (n = 28) with significant promotion and tenure assessment experience.
          Cover page: Scholar Plot: Design and Evaluation of an Information Interface for Faculty Research Performance
          • Article
          • Peer Reviewed
          UC San Francisco Previously Published Works (2023)
          Literature suggests that deficiencies among dental professional students in both knowledge and awareness of human papillomavirus (HPV) and its association with oropharyngeal cancers (OPC), as well as its risk factors implicating the prevalence of HPV, may be due to the lack of HPV-related education during professional schooling. The aim of this study was to assess the effectiveness of an online learning tool to educate dental and dental hygiene students about HPV and its association with OPC, rapidly evolving disease patterns, and dental professionals' role in HPV-associated OPC prevention efforts. A three-section online learning module was developed to improve dental professionals' comfort levels with, and knowledge of, HPV. The participants were recruited to participate in surveys before and after the intervention. Descriptive statistics and chi-square analysis were computed to study the effectiveness of the modules in improving the knowledge of students about this topic. Pre-intervention survey participants totaled 142, and 107 participants answered the post-intervention survey. The majority of the study participants had some baseline understanding of HPV prior to accessing the modules. After reviewing the modules, there was a statistically significant increase in the proportion of respondents who identified OPC (p = 0.01), vaginal cancer (0.02), vulvar cancer (0.04), and penile cancer (0.01) as associated with HPV. A gap in the understanding of HPV vaccine-eligible groups was noted in almost half of the participants; while most participants could correctly identify that boys and girls aged 9-12 years were eligible to get the vaccine, the gap in knowledge in this regard was related to "25-year-old with an abnormal pap result." Due to the evolving nature of this topic, there is a need to find new and effective methods of disseminating HPV-related information among the existing and future dental workforce.
            Cover page: Assessing the Effectiveness of Web-Based Modules on Human Papillomavirus Among Dental and Dental Hygiene Students
            • Article
            • Peer Reviewed
            UC Merced Previously Published Works (2018)
            Born out of the Human Genome Project (HGP), the field of genomics evolved with phenomenal speed into a dominant scientific and business force. While other efforts were intent on estimating the economic impact of the genomics revolution, we shift focus to the social and cultural capital generated by bridging together biology and computing-two of the constitutive disciplines of "genomics". We quantify this capital by measuring the pervasiveness of bio-computing cross-disciplinarity (XD) in genomics research during and after the HGP. To provide interlocking perspectives at the career and epistemic levels, we assembled three data sets to measure XD via (i) the collaboration network between 4190 biology and computing faculty from 155 departments in the United States, (ii) cross-departmental affiliations within a comprehensive set of human genomics publications, and (iii) the application of computational concepts and methods in research published in a preeminent genomics journal. Our results show the following: First, research featuring XD collaborations has higher citation impact than other disciplinary research-an effect observed at both the career and individual article levels. Second, genomics articles featuring XD methods tend to have higher citation impact than epistemically pure articles. Third, XD researchers of computing pedigree are drawn to the biology culture. This statistical evidence acquires deeper meaning when viewed against the organizational and knowledge transfer mechanisms revealed by the data models. With cross-disciplinary initiatives set to dominate the agenda of funding agencies, our case study provides a framework for appreciating the long-term effects of these initiatives on science and its standard-bearers.
              • Article
              • Peer Reviewed
              UC San Francisco Previously Published Works (2018)

              Purpose

              Trachoma is to be eliminated as a public health problem by 2020. To help the process of planning interventions where needed, and to provide a baseline for later comparison, we set out to complete the map of trachoma in Afar, Ethiopia, by estimating trachoma prevalence in evaluation units (EUs) of grouped districts ("woredas").

              Methods

              We conducted seven community-based surveys from August to October 2013, using standardised Global Trachoma Mapping Project (GTMP) survey methodologies.

              Results

              We enumerated 5065 households and 18,177 individuals in seven EUs covering 19 of Afar's 29 woredas; the other ten were not accessible. 16,905 individuals (93.0%) were examined, of whom 9410 (55.7%) were female. One EU incorporating four woredas (Telalak, Dalefage, Dewe, Hadele Ele) was shown to require full implementation of the SAFE strategy for three years before impact survey, with a trachomatous inflammation-follicular (TF) prevalence in 1-9-year-olds of 17.1% (95%CI 9.4-25.5), and a trichiasis prevalence in adults aged ≥15 years of 1.2% (95%CI 0.6-2.0). Five EUs, covering 13 woredas (Berahle, Aba'ala, Dupti, Kurri, Elidihare, Ayesayeta, Afamboo, Bure Mudaitu, Gewane, Amibara, Dulecho, Dalolo, and Konebo), had TF prevalences in children of 5-9.9% and need one round of azithromycin mass treatment and implementation of the F and E components of SAFE before re-survey; three of these EUs had trichiasis prevalences in adults ≥0.2%. The final EU (Mile, Ada'ar) had a sub-threshold TF prevalence and a trichiasis prevalence in adults just >0.2%.

              Conclusion

              Trachoma is a public health problem in Afar, and implementation of the SAFE strategy is required.
                • Article
                • Peer Reviewed
                UC Berkeley Previously Published Works (2021)
                Research over the past decades has demonstrated the explanatory power of emotions, feelings, motivations, moods, and other affective processes when trying to understand and predict how we think and behave. In this consensus article, we ask: has the increasingly recognized impact of affective phenomena ushered in a new era, the era of affectivism?
                  Cover page: The rise of affectivism.
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