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Article
Peer Reviewed

High Asymptomatic Carriage With the Omicron Variant in South Africa

Garrett, Nigel;
Tapley, Asa;
Andriesen, Jessica;
Seocharan, Ishen;
Fisher, Leigh H;
Bunts, Lisa;
Espy, Nicole;
Wallis, Carole L;
Randhawa, April Kaur;
Miner, Maurine D;
Ketter, Nzeera;
Yacovone, Margaret;
Goga, Ameena;
Huang, Yunda;
Hural, John;
Kotze, Philip;
Bekker, Linda Gail;
Gray, Glenda E;
Corey, Lawrence;
Ahmed, Khatija;
Badal-Faesen, Sharlaa;
Barnabas, Shaun;
Brumskine, William;
Comline, Kim;
Diacon, Andreas;
Dubula, Thozama;
Gill, Katherine;
Grobbelaar, Coert;
Innes, Craig;
Kassim, Sheetal;
Kotze, Sheena;
Lazarus, Erica;
Lombaard, Johannes;
Luabeya, Angelique;
Maboa, Rebone Molobane;
Mahoney, Scott;
Mahkaza, Disebo;
Malahleha, Moelo;
Malan, Daniel;
Mngadi, Kathryn;
Naicker, Nivashnee;
Naicker, Vimla;
Naidoo, Logashvari;
Nchabeleng, Maphoshane;
Rassool, Mohammed;
Spooner, Elizabeth;
Tempelman, Hugo;
Mgodi, Nyaradzo;
Dadabhai, Sufia;
Makhema, Joe;
Nuwagaba-Biribonwoha, Harriet;
Samandari, Taraz;
Elyanu, Peter James;
Chilengi, Roma;
Chirenje, Zvavahera;
McElrath, Julie;
Cohen, Myron;
Kublin, James;
Gilbert, Peter;
Peda, Melissa;
Andersen-Nissen, Erica;
Ferrari, Guido;
Villaran, Manuel;
Takalani, Azwidhwi;
Gildea, Marianne;
Nebergall, Michelle;
Sopher, Carrie;
Proulx-Burns, Lori;
Govender, Dhevium;
Sanders, Lisa;
Hanke, Jen;
Baepanye, Kagisho;
Le Roux, Bert;
Wilvich, Haven;
Sripathy, Smitha;
Margineantu, Daciana;
Brown, Valerie;
Linton, Kim;
Howell, Haley;
Noronha, Bianca;
Nikles, Sarah;
Toledano, Alicia;
May, Jeanine;
El-Khorazaty, Jill;
Naidoo, Keshani;
Takalani, Azwidhwi;
Khuto, Kentse;
Mayat, Fatima;
Fairall, Lara;
Sanne, Ian

UC San Francisco Previously Published Works (2022)

We report a 23% asymptomatic severe acute respiratory syndrome coronavirus 2 (SARS CoV-2) Omicron carriage rate in participants being enrolled into a clinical trial in South Africa, 15-fold higher than in trials before Omicron. We also found lower CD4 + T-cell counts in persons with human immunodeficiency virus (HIV) strongly correlated with increased odds of being SARS-CoV-2 polymerase chain reaction (PCR) positive.

Cover page: High Asymptomatic Carriage With the Omicron Variant in South Africa