Background: No physical activity (PA) interventions have specifically targeted Latino men despite marked health disparities in this group. Therefore, we explored the feasibility of designing a PA intervention for Latino men. Methods: We conducted six qualitative interviews with Latino men and used their feedback to modify an existing PA intervention, then conducted a 12-week demonstration trial of the adapted intervention. Results: Themes from interviews included work and family conflicts and preferring team sports. In the demonstration trial of the modified intervention, participants (N = 10) increased PA from 1.3 minutes/week (SD = 4.75) at baseline to 125.5(SD = 154.86) at follow-up (p < .05). Retention was high and participants expressed enthusiasm for the program. Conclusions: Existing interventions could be effectively modified to target physical activity in Latino men. © 2014 by the Men's Studies Press, LLC.