What the Drug Companies Won't Tell You and Your Doctor Doesn't Know: The Alternative Treatments That May Change Your Life--and the Prescriptions That Could Harm You
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About this ebook
Adverse reactions to over-the-counter and prescription drugs are currently estimated to kill more than 100,000 Americans a year, making it the fourth leading cause of death in the United States behind cancer, heart disease, and stroke.
Drawing on more than twenty years of scientific research, Dr. Michael T. Murray reveals how the pharmaceutical treatments of the most common diseases that plague our society are often ineffective and result in serious, widespread side effects—and then explains how natural treatments can help us avoid them.
What the Drug Companies Won’t Tell You and Your Doctor Doesn’t Know makes clear that we must radically reevaluate the way that we take care of ourselves, and Dr. Murray provides clear guidance on the steps necessary to help you lead a fitter, happier, and healthier life.
Michael T. Murray
Michael T. Murray, ND, is a doctor of naturopathy, a field of alternative medicine that seeks to harness the power of nature to prevent illness and achieve the highest level of health possible. He is the author of more than thirty books, including the acclaimed bestsellers The Encyclopedia of Natural Medicine (Third Edition) and The Encyclopedia of Healing Foods (co-authored with Dr. Joseph Pizzorno). He is regarded as the world authority on natural medicine and appears regularly in national media, including The Dr. Oz Show. He is a health food industry consultant, researcher, educator, and lecturer. For more information visit his information portal, DoctorMurray.com.
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What the Drug Companies Won't Tell You and Your Doctor Doesn't Know - Michael T. Murray
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In loving memory of my father, Clifford G. Murray, Jr.
PROLOGUE
"The enemy of the conventional wisdom is
not ideas but the march of events."
—John Kenneth Galbraith
THE TERM CONVENTIONAL WISDOM
was coined by the noted economist John Kenneth Galbraith in his book The Affluent Society, in 1958. According to Galbraith, conventional wisdom is established if it is simple, convenient, comfortable, and comforting—though not necessarily true. Galbraith also said, We associate truth with convenience, with what most closely accords with self-interest or personal well-being.
People want to believe conventional wisdom because it is indeed so simple, convenient, comfortable and comforting, even if it may not be true. And once conventional wisdom on any topic is accepted, it becomes difficult to prove otherwise.
In the United States, the medical establishment has created the conventional wisdom that drug-oriented medicine is the best form of medicine. Yet many of these drugs only make us feel better in the short term, while exposing us to the risk of dependency, producing side effects worse than the condition being treated, or actually causing the condition to worsen. These substantial risks, and the rising costs associated with a drug-oriented medical system, are creating an opportunity for change.
Change is definitely coming; in fact, we are in the midst of it. There has been a subtle revolution in medicine for years, and a new paradigm is emerging. A paradigm is a model used to explain events. As our understanding of the environment and the human body evolves, new paradigms—new explanations—are developed. For example, in physics the cause-and-effect explanations of Descartes and Newton were superseded by quantum mechanics, Einstein’s theory of relativity, and theoretical physics, which takes into consideration the tremendous interconnectedness of the universe.
The new paradigm in medicine also focuses on interconnectedness: in this case, of body, mind, emotions, social factors, and the environment in determining the status of an individual’s health. And whereas the old paradigm viewed the body basically as a machine that can be fixed best with drugs and surgery, in the new, emerging model these measures are secondary to natural, noninvasive, techniques to promote health and healing. The relationship between the physician and the patient is also evolving. The era of the physician as a demigod is over. The era of self-empowerment is beginning.
NATUROPATHIC MEDICINE
By definition and philosophy most conventional medical doctors (M.D.s) practice allopathic medicine—the system of medicine that focuses primarily on treating disease rather than promoting health. In contrast, you may have noticed the N.D. after my name on the cover. This signifies that I am a naturopathic doctor. I graduated from Bastyr University with a doctorate in naturopathic medicine—a system that emphasizes prevention, treatment, and the promotion of optimal health through the use of natural, nontoxic therapies. The scope of practice of an N.D. includes all aspects of family and primary care, from pediatrics to geriatrics, as well as the full range of human health conditions including cancer. Naturopathic medicine is based on seven time-tested principles:
First, do no harm. N.D.s seek to do no harm with medical treatment; therefore, they employ safe and effective natural therapies.
Employ the healing power of nature. N.D.s believe that the body has considerable power to heal itself. The role of the physician is to facilitate and enhance this process with the aid of natural, nontoxic therapies.
Identify and treat the cause. N.D.s are trained to seek the underlying causes of a disease rather than simply suppress the symptoms. Symptoms are viewed as expressions of the body’s attempt to heal, whereas causes can spring from physical, mental-emotional, and spiritual levels.
Treat the whole person. N.D.s are trained to view an individual as a whole, composed of a complex set of physical, mental-emotional, spiritual, social, and other factors.
The physician is a teacher. The word doctor
comes from the Latin docere, which means to teach.
N.D.s view our roles as primarily those of teachers: to educate, empower, and inspire our patients to assume more personal responsibility for their health by adopting a positive attitude, lifestyle, and diet.
Prevention is the best cure. N.D.s believe that an ounce of prevention is worth much more than a pound of cure. With regard to cancer, this saying is especially true. We are specialists in preventive medicine. Real prevention of death caused by cancer is achieved not only by early diagnosis, but also through education and encouraging life habits that support health.
Establish health and wellness. Our primary goals for our patients are to establish and maintain optimum health and to promote wellness. Health
is defined as the state of optimal physical, mental, emotional, and spiritual well-being; wellness
is defined as a state of health, characterized by a positive emotional state. Naturopathic physicians strive to increase the patient’s level of wellness, regardless of the level of health or disease. Even in cases of severe disease such as cancer, a high level of wellness can often be achieved.
THE NEED FOR RATIONAL MEDICINE
When people refer to me as an expert in alternative medicine, I usually correct them. I am a proponent of what I like to describe as rational medicine, which combines the best of both conventional medicine and alternative methods. In fact, I believe a system is evolving and emerging that incorporates the best of both conventional medicine and what is currently labeled alternative
medicine. My goal is to speed up this process. Just as we now view the conventional treatments in vogue at the beginning of the nineteenth century (e.g., mercury, bloodletting, and purges) as having been irrational, counterproductive, and in many cases harmful, so too will many of today’s conventional treatments be judged in a similar light by the medical circles of tomorrow. However, there are many conventional medical practices and drugs that are completely rational. In fact, it would be irrational not to take advantage of modern medicine when appropriate. That said, there is no question that the majority of health complaints for which patients see doctors originate with dietary and lifestyle factors. Trying to treat the symptoms with a drug (a biochemical Band-Aid) often fails to address the underlying cause and as a result leads to side effects. Clearly, a more rational and truthful approach to health care is needed.
SOME WORDS OF CAUTION
Although this book discusses numerous natural medicines and approaches, it is not intended as a substitute for appropriate medical care. Please keep the following in mind as you read:
Do not self-diagnose. Proper medical care is critical to good health. If you have concerns about any subject discussed in this book, please consult a physician, preferably a naturopathic doctor (N.D.), a nutritionally oriented medical doctor (M.D.) or doctor of osteopathy (D.O.), or some other specialist in natural health care.
Make your physician aware of all the nutritional supplements or herbal products you are currently taking, to avoid possible negative interactions with any drugs you take.
If you are currently taking prescription medications, you absolutely must work with your doctor before discontinuing any drug or altering any drug regimen.
Most health conditions require a multifactorial solution: medical, nutritional, and lifestyle changes. Do not rely solely on a single area of focus. You can’t just take pills and not change your diet, or follow a diet and take pills but ignore lifestyle issues. Any truly effective approach to health must be truly integrated.
MY HOPE
It is my sincere hope that you—and those you care about—will use the information provided in the following pages to achieve greater health and happiness. I also hope that you can all become advocates of change. The nineteenth-century philosopher Arthur Schopenhauer observed that truth passes through three phases: first, it is ridiculed; second, it is fiercely and violently opposed; and third, it becomes self-evident. However, this three-part progression does not happen automatically or magically. As Dr. Martin Luther King, Jr., said, duration is not enough: the mere passage of time does not create change. It requires ordinary people envisioning, acting and constructing the future. Each of us can help bring this progression into being—in part, by being phase three
people currently living in a phase one
and phase two
world.
Live in good health with passion and joy!
Michael T. Murray, N.D.
1
A MATTER OF TRUST—MAKING MEDICINE OR MAKING MONEY?
"Where large sums of money are concerned,
it is advisable to trust nobody."
—Agatha Christie
IS IT REALLY POSSIBLE that American baby boomers and younger generations have been led down a road to poor health by the pharmaceutical industry and conventional medical practice? Have the very industries, organizations, and medical doctors responsible for designing our health care system created the catastrophe of skyrocketing medical costs? Are the drug companies so powerful that they exert virtually complete control over the Food and Drug Administration (FDA), medical schools, prestigious medical journals, and continuing medical education for physicians? Is it true that adverse reactions to over-the-counter (OTC) and prescription drugs are estimated to kill over 100,000 Americans a year, making these reactions the fourth-largest cause of death in the United States, behind cancer, heart disease, and strokes?
The answer to all these questions is yes. The pharmaceutical industry and the medical monopoly have created a health care crisis in America. In this book, we will, together, take a peek behind the curtain to expose some of the fallacies and shortcomings of many popular medications. It is absolutely true that most of us have been helped in almost magical ways by the wonders of modern medicine, but the reality is that conventional medicine has also created a lack of personal accountability and a complete reliance on little pills to cure what ails us. We now have on our hands a modern epidemic, consisting not only of diseases that are clearly a result of diet and lifestyle, but also of diseases due to the side effects of drugs used in their treatment.
The United States has by far the highest per capita use of conventional medicines and uses over more than 40 percent of all of the drugs produced in the world each year, according to the World Health Organization (WHO); but we are only forty-second in terms of life expectancy. We are definitely not getting our money’s worth from our medicine. It is easy to demonize the greedy pharmaceutical industry, but the problem is much deeper than that. It is also easy to say that most medical doctors have simply been unknowing pawns in the drug companies’ game of profits, never realizing that they have been led to perpetuate lies, half-truths, and incomplete science; but the reality is that the medical profession has done a questionable job in protecting the health of the patient. In fact, many doctors are willing players in the game. They do not mind. It represents easy money. The average income for a medical doctor is more than $200,000 per year, and many specialists, such as radiologists and heart surgeons, have an average income of more than $300,000 per year. It could be that there is one very big reason why many medical doctors do not practice preventive medicine—money. The average yearly income for a member of the American College of Preventive Medicine, a group of preventive medical doctors, is $100,000—a good income, but considerably less than half the average income for other medical specialties.
Also, it is estimated that drug companies spend more than $57.5 billion a year marketing to physicians. This figure includes about $14 billion for what is referred to in the industry as unmonitored promotion
it can include lavish vacations and getaways, ostensibly continuing medical education. With about 700,000 practicing physicians in the United States, it is estimated that the drug industry spends about $60,000 in marketing per physician.¹
Do the Drug Companies Spend More on Marketing or Research?
According to a very detailed analysis by two Canadian researchers, Marc-André Gagnon and Joel Lexchin, The Cost of Pushing Pills: A New Estimate of Pharmaceutical Promotion Expenditures in the United States,
¹ drug companies spend twice as much money on marketing as on research and development. Now, the U.S. General Accountability Office (GAO) says otherwise. Why the discrepancy? Well, it turns out that the data supplied to the GAO are from IMS, a firm specializing in pharmaceutical market intelligence. There are many concerns about the accuracy of the IMS data, chief among them being that the data are derived by asking the drug companies to supply them. The bottom line is that the IMS data are simply not consistent with other published sources, including data provided by the U.S. Office of Technology Assessment as well as information gathered from year-end financial reports from the drug companies themselves.²
DRUG COMPANIES, PROFITS, AND THE FDA
If anyone knows the depth of the deceit and false promises heaped on Americans by drug companies, it is Marcia Angell, M.D., former editor in chief of the New England Journal of Medicine, one of the most respected medical journals in the world. According to Dr. Angell, the pharmaceutical industry has moved very far from its original high purpose of discovering and producing useful new drugs. Now primarily a marketing machine to sell drugs of dubious benefit, this industry uses its wealth and power to coopt every institution that might stand in its way, including the U.S. Congress, the Food and Drug Administration, academic medical centers, and the medical profession itself.
³
There is now considerable evidence that the drug companies exert significant control over the FDA and the drug approval process. More than half of the experts hired to advise the FDA on the safety and effectiveness of drugs have financial relationships with drug companies that will be helped or hurt by their decisions. Federal law generally prohibits the FDA from using experts with financial conflicts of interest, but the FDA waived this rule 800 times in a 15-month period from January 1998 to June 2000. In an analysis of all advisory panel meetings from 2001 to 2004, at least one member had a financial link to the drug’s maker or a competitor in 73 percent of the meetings.¹, ² The potential damage from such ties was exemplified in 2005, when the FDA convened a meeting to discuss the toxicity of the COX-2 inhibitors Vioxx, Celebrex, and Bextra. Had the ten committee members with ties to industry been precluded from voting, the committee would have voted against continued marketing for Vioxx and Bextra; instead, all three drugs received favorable votes.³, ⁴ As a result these potentially dangerous drugs were allowed to stay on the market. That trend has created a huge problem, because 20 percent of all approved drugs over the last 25 years were later found to have serious side effects leading either to the withdrawal of the drug from market or to warning labels noting these serious side effects. The drug companies could afford to take a gamble on drugs like Vioxx, Celebrex, Avandia, OxyContin, and others because of the huge profits they could generate.
Since the 1950s, drugs have been the most profitable industry in America. In December 1959, the last year of the Eisenhower administration, the Senate Subcommittee on Antitrust and Monopoly reported on a yearlong investigation of the drug industry with the declaration that the public was not only being overcharged for drugs but was being ripped off for useless and sometimes harmful medicines. Three charges were leveled at the drug industry by the subcommittee: (1) Patents sustained predatory prices and excessive margins. (2) Costs and prices were extravagantly increased in order to fund marketing expenditures. (3) Most of the industry’s new products were no more effective than lower-priced, established drugs on the market. Back in the 1950s, this report changed the image of drug companies: the companies had been seen as employing lifesaving researchers in white coats
but were now seen as employing primarily zealous sales reps in cars.
Has the situation changed in the last 50 years? Yes: it has gotten much better for the drug companies, at the public’s expense. During the past 50 years drug costs have skyrocketed at a rate five times inflation. In 1960, the drug industry had a profit margin of 10.6 percent of sales. By 1992, this had increased to 13 percent. In 2005, it was 18 percent. Pfizer, the world’s number one drug company, had a profit margin of 26 percent of sales.
In 1980, the average prescription cost $6.52; in 1992 the cost was $22.50; in 2006 it was $50.17. Drug costs are higher in the United States than anywhere else in the world. Most major industrial nations apply profit control to limit how much a drug company can charge for a drug. Because most drug companies market the same drug throughout the world, they rely on the United States for the bulk of their profits. In the United States, drug companies can increase the price of drugs without fear, because there is very little competition. In fact, there is more cooperation between drug companies to keep prices high than there is price competitiveness.³, ⁴
HIGHER-PRICED DRUGS + MORE PRESCRIPTIONS WRITTEN = HUGE PROFITS FOR DRUG COMPANIES
The simple sum expressed above is astronomical in real life because more people than ever before are being placed on high-priced drugs. For example, roughly 4 billion prescriptions were filled last year, about 12 prescriptions for every person in the United States. Are all these prescriptions necessary? Remember that the United States uses more than 40 percent of all the drugs in the world but ranks only forty-second in life expectancy; also, it ranks only thirty-seventh in the quality of its health system, according to WHO. The high cost of drugs is bankrupting our elderly population, and our society. The number of seniors who depend on prescription drugs is unbearable. In 1992, the average senior received 19.6 prescriptions per year; in 2005, that number had nearly doubled, to 34.4. The average person over the age of 55 is on eight or more prescription drugs at any one time.
According to a study by Fidelity Investment released in March 2006, a 65-year-old couple retiring today will need, on average, $200,000 set aside to pay for medical costs during retirement. A big chunk of that $200,000 will go to pay for expensive drugs that produce questionable results and raise considerable safety issues. For example, the current treatment of type 2 diabetes is very absurd. Now an American epidemic, diabetes is also a source of huge profits for drug companies, yet the research findings are quite clear—oral medications to treat type 2 diabetes do not alter the long-term development of the disease. Although the drugs are quite effective in the short term, they create a false sense of security: they ultimately fail and are then prescribed at higher dosages or in combination with other drugs, leading to increased mortality. That is right; the long-term use of these drugs is actually associated with an earlier death, compared with mortality in control groups of diabetics who are not given the drugs. Here are some additional facts:
It is estimated that 70 percent of patients with chronic daily headaches suffer from drug-induced headaches.
Sleeping pills interfere with normal sleep cycles, produce numerous side effects, and are addictive.
Aspirin, ibuprofen, and other nonsteroidal drugs (NSAIDs) used for arthritis lead to joint destruction by inhibiting the formation of cartilage.
NSAIDs cause 16,500 deaths in the United States annually, and more than 100,000 Americans are hospitalized because of side effects.
Acetaminophen overdose is the leading cause of acute liver failure and causes 10 percent of all cases of kidney failure.
Drugs like Paxil, Zoloft, and Prozac contribute to obesity, but weight gain is not listed as a common side effect of these drugs.
WHY HAVE HEALTH CARE COSTS SKYROCKETED?
In addition to higher-priced drugs, the reasons often cited to explain the tremendous rise in health care costs include these:
Why Was the FDA Slow to Warn Patients about the Popular Diabetes Medication Avandia?
GlaxoSmithKline (GSK), the makers of the popular diabetes drug Avandia (rosiglitazone maleate) informed the FDA as early as 2005 that this drug was associated with a 30 percent increase in the risk of heart disease. Instead of acting immediately on this important information and warning patients of the potential risk, GSK took until June 2007, when a study was published in the New England Journal of Medicine, to bring this risk to light.⁵ The lead researcher Steven Nissen, M.D., from the Cleveland Clinic, wrote in his report that both GlaxoSmithKline and the FDA should have taken (but didn’t take) the necessary steps to adequately warn people using Avandia of the risks to their health. An examination of data from a pool of 42 studies provided by GSK showed that there was a 43 percent increase in the number of heart attacks and a 64 percent increase in the risk of dying from heart disease among people with type 2 diabetes taking Avandia, compared with people given a placebo. Keep in mind that the reason drugs are prescribed to lower blood sugar is to prevent the complications of diabetes, the most important of which is heart disease.
Given the facts that in 2006 alone, doctors in the United States wrote 13 million prescriptions for Avandia and that the results of this study were so damning, it is estimated that as many as 16,000 legal claims could be made against GSK in response to the study. But even though the FDA shares equal blame for allowing these deaths to happen, no legal action will be made against it.
We have too many doctors. The ratio of practicing medical doctors to the population went from 151 doctors per 100,000 people in 1970 to 245 per 100,000 in 1992, an increase in ratio of 62 percent.
We have too many medical specialists. Fifty years ago, specialists were 30 percent of the physician workforce; today, specialists account for 70 to 80 percent.
There are too many unnecessary visits to doctors, medical procedures, surgeries, and drugs being administered by doctors. Currently, medical analysts estimate that 36 percent of physician visits are unnecessary, 56 percent of surgeries are unnecessary, 15 percent of hospital outpatient visits are unnecessary, and half of all time spent in hospitals is not medically indicated.
One of the most disturbing statistics is that there is a direct correlation between the ratio of surgeons in an area and the percentage of the local population receiving surgeries. One research study found that an area with 4.5 surgeons per 10,000 population experienced 940 operations per 10,000 whereas an area with 2.5 surgeons per 10,000 experienced 590 operations per 10,000.⁶ In other words, when the concentration of surgeons doubles, so does the rate of surgeries. It makes sense, doesn’t it? After all, these surgeons need to perform surgeries to cover overhead and maintain their desired income. The problem is apparently worse for especially expensive surgeries. For example, according to a noted Harvard cardiologist and published studies in the Journal of the American Medical Association, more than 80 percent of coronary angioplasty and bypass operations are not necessary.⁷ These surgical procedures cost, on average, $40,000. The rise in expensive hospital-based procedures such as coronary artery bypass operations prescribed by highly specialized physicians is considered by health economists to be the primary cause of our escalating health care costs.
SELLING SICKNESS
As if it were not enough to gouge the pocketbooks of Americans for drugs to treat sickness, the drug companies have used their influence to narrow the boundaries of what is normal for conditions such as cholesterol and blood pressure, so that they can cast a bigger net and get doctors to prescribe their drugs to more patients. The goal of the drug companies is transparent and has been expertly revealed in Selling Sickness: How the World’s Biggest Pharmaceutical Companies Are Turning Us All into Patients, by Ray Moynihan and Alan Cassells.
The ultimate strategy of Merck, one of the largest drug companies in the world, was outlined more than 30 years ago when Henry Gadsden, the head of Merck at the time, was interviewed by Fortune magazine. Gasden said he wanted Merck to be more like Wrigley gum, that it was his dream to make drugs for healthy people so that Merck could sell to everyone.⁸ This dream is now nearly reality, if you take a look at the number of people currently taking statin medications to lower cholesterol. By the way, the first statin drug to be marketed was Merck’s Mevocor (lovastatin).
Selling Addiction
Oxycodone is a potent and highly addictive synthetic opiate-like pain medication marketed under the proprietary names Percocet, Combunox, Roxicodone, OxyContin, and as generic alternatives. Of these, the most notorious is OxyContin (the name is actually short for Oxycodone Continuous release) popularly referred to as pharmaceutical heroin
and marketed as a miracle drug for people with chronic pain. On May 10, 2007, Purdue Pharma—the company that makes OxyContin—and three current and former executives pleaded guilty in a U.S. court to criminal charges that they misled regulators, doctors, and patients by falsely claiming that OxyContin was less addictive, less subject to abuse, and less likely to cause withdrawal symptoms than other pain medications. To resolve criminal and civil charges related to the drug’s misbranding,
Purdue Frederick—the parent company of Purdue Pharma—and its top three executives agreed to pay about $634 million in fines and other charges, one of the largest amounts ever paid by a drug company in such a case. OxyContin was launched in 1995, and its annual sales reached approximately $2 billion prior to the arrival of generic products in 2004 and are still over $1 billion annually. So, although $634 million seems like a huge fine, it was still not as high as the drug company’s profits.
Sales of statin drugs such as Lipitor, Crestor, and Pravachol have reached unbelievable heights; these are by far the best-selling category of drugs. How these drugs rose in popularity serves as a model for the entire drug industry and is explained in Chapter 7. One strategy of the drug companies selling statins was to expand the number of people who met the criterion of high cholesterol.
Every time the level of cholesterol