The Accelerators (Drs. Matt Spraker and Simul Parikh) host Sam Mazin, Ph.D. and Sean Shirvani, MD, CTO and CMO of RefleXion. This Rad Onc startup have created a linear accelerator with on board PET/CT. This allows for SCINTIX biology-guided radiotherapy for bone and lung disease. Sam and Sean join the show to share their story in medical entrepreneurship, discuss the technology, and their vision for the future of our field. Why is SCINTIX any better than fusing a PET/CT to a standard CT simulation? PET/CT on board and in real time offers potential safety advantages and opportunities for personalized therapy. Many would argue that novel radio-molecules and total metastatic ablation are the future of our field. Sam and Sean invite us to think bigger and a lot more creatively about how that future might look for our patients. Here are some other things that were discussed during the show.Bob Timmerman and Nina Sanford on TAP, Parts 1 and 2RefleXion Research Program InformationShankar Siva and others with a good discussion about total metastatic ablation, XSCINTIX receives FDA clearance, RefleXion