ISSN |
2220-6132 (online) |
Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
Copyright |
©The Author(s) 2022. Published by Baishideng Publishing Group Inc. All rights reserved. |
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Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
Website |
http://www.wjgnet.com |
Category |
Medicine, Research & Experimental |
Manuscript Type |
Minireviews |
Article Title |
Photobiomodulation therapy for osteoarthritis: Mechanisms of action
|
Manuscript Source |
Unsolicited Manuscript |
All Author List |
Fábio Pericinoto Giolo, Gabriel Silva Santos, Victor Fontes Pacheco, Stephany Cares Huber, Kaue Franco Malange, Bruno Lima Rodrigues, Fernanda Bassora, Tomas Mosaner, Gabriel Azzini, Lucas Leite Ribeiro, Carlos Amilcar Parada and José Fábio Santos Duarte Lana |
Funding Agency and Grant Number |
|
Corresponding Author |
Gabriel Silva Santos, BSc, Academic Research, Instructor, Lecturer, Research Scientist, Technician, Biomedical Science, Brazilian Institute of Regenerative Medicine, 1386 Presidente Kennedy Avenue , Indaiatuba 13334-170, Brazil. [email protected] |
Key Words |
Photobiomodulation; Low-level laser therapy; Osteoarthritis; Inflammation; Regenerative medicine |
Core Tip |
Photobiomodulation (PBM) is a non-invasive therapeutic modality with demonstrated effects in regenerative medicine. In the field of orthopedics, in particular, PBM at various wavelengths has demonstrated the capacity to trigger multiple biological effects associated with protective mechanisms in musculoskeletal tissues. These responses include proliferation, differentiation and expression of proteins associated with stable cell cycles. Additionally, PBM can also modulate oxidative stress, inflammation and pain by exerting regulatory effects on immune cells and blocking the transmission of pain through sensory neuron fibers. |
Publish Date |
2022-08-25 06:29 |
Citation |
Giolo FP, Santos GS, Pacheco VF, Huber SC, Malange KF, Rodrigues BL, Bassora F, Mosaner T, Azzini G, Ribeiro LL, Parada CA, Lana JFSD. Photobiomodulation therapy for osteoarthritis: Mechanisms of action. World J Transl Med 2022; 10(3): 29-42 |
URL |
https://www.wjgnet.com/2220-6132/full/v10/i3/29.htm |
DOI |
https://dx.doi.org/10.5528/wjtm.v10.i3.29 |