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Explores the high-pressure experiences of first responders who are thrust into the most frightening, shocking, and heart-stopping situations, day after day.

A rookie FBI agent is recruited as the new violent crimes task force profiler to solve murder cases.

Cheryl Anne Monroe, a pregnant woman, is found dead in Studio City after suffering systemic shock and her baby cut from her - but it is not thought the baby survived due to the brutal way Cheryl was cut. The team's investigation lead them to Betty Scarwid - who miscarried two months previously - and who was in Cheryl's yoga class. The increasingly delusional Betty attacks another pregnant woman and takes her baby son and goes to meet her boyfriend Scott Bossi who's back from Iraq. When Scott confronts her about who's baby she has she stabs him and goes to the house that she and Scott bought where she buries the baby alive. It is up to Paul to find out where the baby is buried before he dies. Paul and Karen finally talk about their lost baby.

Superintendent Glenn Terry talks to the team but they are decidedly unresponsive to his overtures. A female body is found in the Los Angeles River at Lincoln Heights with her fingernails removed, needles and kaleidoscope shapes stuck in her eyes and stun gun marks at her neck. The killing is an exact replica of a previous killing. When a third victim is found they find that it points to an elderly attacker who is eventually identified as Max Stern. Unable to apprehend him and requiring guidance Rebecca goes to see Web. Unknown to her she is photographed leaving and the team are not happy that she was caught. Meanwhile, Web does his own investigation and hires prostitute Holly Lynn Krandall to lure Max Stern out but he is taken into custody by Terry's men and it is up to his old team to find Holly before she becomes the next victim. Web gets his job back at the bureau.

Eight year old Henry Olsen from the Hidden Harbor gated security-conscious community is found by his mother face down in their pool. A postmortem shows that he had been gutted before being dumped in the pool. Rebecca and Paul are the lead in the case and they quickly arrest grounds-keeper Teddy Bunch based on evidence supplied by Henry's friend Madison St. Clair. But Rebecca quickly notices that Madison is putting on an act and lying about the events of the night and sets about proving it but she hadn't figured how much a psychopath Madison really is.

The team investigate the origins of a snuff slasher film which surfaced at a children's birthday party and the disappearance of the actress in the film Angelica Sandavol. Meanwhile, Rebecca hesitates about going on a date with Corey.

Rebecca and the team probe the disappearance of the Anderson and Presley families who went missing in the Angeles National Forest along Highway 39. The team quickly arrest Karl Robie Jr. but on the way to find the Presley family the helicopter carrying Danny, Rebecca and Karl crashes and so ensues a frantic bid to find Rebecca before Karl does. Rebecca is haunted by visions of her past abduction by Pony Man.

The team investigate a string of apparent suicides which are now ruled as homicides. Rebecca's investigation leads her to a suicide hot line and determined to find out about the staged suicides she goes undercover as a potential suicide victim.

The team investigate a series of arson's which lead them to suspect Louis Salt but the cases trigger events in Rebecca's past life as Becky George.

Whilst investigating pro-anorexia websites and linking them to missing women on her own Rebecca is lured by a false lead, drugged and imprisoned by a morbidly obese man named Ronald Ewing. It's now up to the team to get to her before Ronald kills Rebecca like the previous missing women.

Rebecca is used as bait at the Pyramid Nightclub to lure a serial rapist and murderer who's victims were last seen there. Rebecca begins a relationship with Pyramid bartender Corey Hall but events nearly put a halt to their relationship.

Lisa Aaron is found dead in her bedroom with a .38 caliber shot to the head and with her heart removed and a small romantic card inserted in her mouth. Paul is convinced that it is the work of serial killer Billy Ray Pope (and his first case) but Web tells him that he was in prison at the time of the murder. Investigations into the case puts Paul's initial case in jeopardy after a witness recants their initial testimony and the case is set aside. Paul is taken off the case and does his own investigation and finds out that Web framed Pope for the initial killings as he couldn't get any evidence to stick. Paul's wife Karen loses their baby in a car accident after she goes looking for him. Web tenders his notice to Superintendent Glenn Terry after the case is solved.

Athena enlists the 118's help when a teenager speeds out of control on the freeway; A routine traffic stop uncovers a shocking kidnapping; Buck struggles with his recovery.

Owen Strand, the lone survivor of his Manhattan firehouse on 9/11, takes his progressive philosophies of life and firefighting down to Austin, Texas, where he helps the firefighters of Firehouse 126 start anew.

Owen helps T.K. reconcile the past to help his future; Michelle learns the full truth about Iris.

The crew races to an outbreak of mercury poisoning leaving its victims in a zombie-like state; Owen must come to terms with his illness; Michelle follows a new lead on her missing sister.

A massive tsunami hits the Santa Monica Pier, placing Buck and Christopher's lives in danger.

Athena, Maddie, Bobby, and the 118 race to save lives after a massive tsunami hits the Santa Monica Pier; Buck fears the worst when Christopher goes missing.

Athena takes action after her family experiences a traumatic traffic stop; Buck's suit against the city goes to arbitration; Eddie turns to Lena in his struggles with his anger issues.

Athena and the 118 respond to bizarre emergency calls on Halloween; Maddie remains convinced that she is doing the right thing in taking a 911 call into her own hands.

Emergencies include an accident at a grain silo and a steak eating contest; Owen helps Michelle uncover new information about her sister's disappearance.

A massive tornado sweeps through Austin, as the crew races to save those in its path.

The crew races to a brawl at a male strip club, a fire at a bull semen factory and a protest; Grace tries to reconnect with Judd; Owen faces the consequences of his chemo.

Emergencies include a ride-share trip gone awry, a farming accident and a memorial service that may turn into another funeral; Owen unexpectedly bonds with the former Captain of the 126; The crew help Mateo with his written exams.

The crew deal with a runaway bull at a used car lot and an apparent electrocution at the hands of an LA transplant; Michelle gets the strongest lead yet on her missing sister.