Dogs almost always have dewclaws on the inside of the front legs and occasionally also on the hind legs.^[1][3] Unlike front dewclaws, rear dewclaws tend to have little bone or muscle structure in most breeds. It is normal, although not biologically necessary, that certain breeds will have more than one dewclaw on the same paw. One of these dewclaws will most likely be poorly connected to the leg, and is often surgically removed. When a dog has extra dewclaws in addition to the usual one on each front leg, the dog is said to be double dewclawed. For certain dog breeds, a dewclaw is considered a necessity, e.g., a Beauceron for sheep herding and for navigating snowy terrain.^[1] As such, there is some debate about whether a dewclaw helps dogs gain traction when they run because, in some dogs, the dewclaw makes contact when they are running and the nail on the dewclaw often wears down in the same way that the nails on their other toes do, from contact with the ground. In many dogs, the dewclaws never contact the ground. In this case, the dewclaw's nail never wears away, and it is often trimmed to maintain it at a safe length.

The dewclaws are not dead appendages. They can be used to lightly grip bones and other items that dogs hold with the paws. In some dogs, these claws may not appear to be connected to the leg at all except by a flap of skin; in such dogs, the claws do not have a use for gripping as the claw can easily fold or turn.^[4]

Canids have four claws on the rear feet,^[5] although some domestic dog breeds or individuals have an additional claw, or more rarely two, as is the case with the Beauceron. A more technical term for these additional digits on the rear legs is hind-limb-specific preaxial polydactyly.^[6] Several genetic mechanisms can cause rear dewclaws; they involve the LMBR1 gene and related parts of the genome.^[6] Rear dewclaws often have no phalanx bones and are attached by skin only.^[7]

There is some debate as to whether dewclaws should be surgically removed.^[1][8] The argument for removal states that dewclaws are a weak digit, barely attached to the leg, and thus they can rip partway off or easily catch on something and break, which can be painful and prone to infection. Dewclaw removal is most easily performed when the dog is young, around 2–5 days of age. It can also be performed on older dogs if necessary though the surgery may be more difficult then. The surgery is fairly straightforward and may be done with local anesthetics if the digit is not well connected to the leg. Many dogs cannot resist licking the surgery site in the weeks following the procedure, so an Elizabethan collar or bitterant may be used to curtail this behavior, thus preventing infection.^{[citation needed]}

Some pups are commonly sold by breeders "dew-clawed", that is with the dewclaws removed (as by a veterinarian) for perceived health and safety reasons. A few breed standards, such as that for Portuguese Water Dogs, also call for it.

Based on stop-action photographs, veterinarian M. Christine Zink of Johns Hopkins University believes that the entire front foot, including the dewclaws, contacts the ground while running. During running, the dewclaw digs into the ground preventing twisting or torque on the rest of the leg. Several tendons connect the front dewclaw to muscles in the lower leg, further demonstrating the front dewclaws' functionality. There are indications that dogs without dewclaws have more foot injuries and are more prone to arthritis. Zink recommends "for working dogs it is best for the dewclaws not to be amputated. If the dewclaw does suffer a traumatic injury, the problem can be dealt with at that time, including amputation if needed."^[2]

Members of the cat family – including domestic cats^[9] and wild cats like the lion^[10] – have dewclaws. Generally, a dewclaw grows on the inside of each front leg but not on either hind leg.^[11]

The dewclaw on cats is not vestigial. Wild felids use the dewclaw in hunting, where it provides an additional claw with which to catch and hold prey.^[10]

Hoofed animals walk on the tips of special toes, the hooves. Cloven-hoofed animals walk on a central pair of hooves, but many also have an outer pair of dewclaws on each foot. These are somewhat farther up the leg than the main hooves, and similar in structure to them.^[12] In some species (such as cattle) the dewclaws are much smaller than the hooves and never touch the ground. In others (such as pigs and many deer), they are only a little smaller than the hooves, and may reach the ground in soft conditions or when jumping. Some hoofed animals (such as giraffes and modern horses) have no dewclaws. Video evidence suggests some animals use dewclaws in grooming or scratching themselves or to have better grasp during mating.^{[citation needed]}