Looking for New Biochemical Mechanisms in Cancer: The New Dawn in the Omics Sciences

A special issue of Cancers (ISSN 2072-6694). This special issue belongs to the section "Molecular Cancer Biology".

Deadline for manuscript submissions: 26 June 2025 | Viewed by 604

Special Issue Editors


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Guest Editor
1. Department of Precision Medicine, University of Campania "Luigi Vanvitelli", 80138 Naples, Italy
2. Biogem Scarl, Institute of Genetic Research, 83031 Ariano Irpino, Italy
Interests: non-coding RNA; circulating biomarkers; nanotechnology; drug delivery; signal transduction; cell death mechanisms; target therapy; next generation sequencing; cancer; laryngeal cancer, glioblastoma, hepatocellular carcinoma
Special Issues, Collections and Topics in MDPI journals

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Guest Editor
Department of Life and Health Sciences, Via del Casale di San Pio V, Link Campus University, 44, 00165 Rome, Italy
Interests: cancer research; non-coding RNAs; biomarkers research; liquid biopsy; hepatocellular carcinoma; laryngeal cancer

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Guest Editor
Department of Precision Medicine, University of Campania “Luigi Vanvitelli”, 80138 Naples, Italy
Interests: molecular biology; cell biology; biochemistry; bioinformatic
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Collegues,

In recent years, continued growth in the field of omics science, in terms of the understanding of the biological processes observed in human health and diseases, has been reported. Developments in sequencing and progress in high-throughput computational analyses have allowed us to observe the incredible complexity of the molecular context of cancers with unsuspected diversity within the same tumor histological subtype, as well as the spatial and temporal heterogeneity of tumors.

The integration of multiple biological layers of omics studies brought oncology into a new paradigm from the genetic profile of cancer and metastases, improving survival times and promoting selective therapeutic opportunities for precision medicine.

This Special Issue aims to discuss the challenges and future directions for dissecting the tumor environment and host–tumor interaction using multi-omics techniques. Thanks to the development of both experimental protocols and computational methods, the implementation of multi-omics strategies into the clinical workflow will likely introduce benefits in the clinical management of cancers, including decision-making guidance and patient outcome improvement. Another important aspect developed in the present Special Issue will be the study of the role of these specific genetic and epigenetic signatures in the determination of signal transduction pathways regulating both the proliferation and metastases of cancer cells independently from their histological and organ origins. Moreover, we invite our colleagues to show how multi-omics data can be combined with clinical data for the identification of prognostic and treatment-specific biomarkers, paving the way for personalized therapy.

In this Special Issue, original research articles and reviews are welcome.

We look forward to receiving your contributions.

Dr. Alessia Maria Cossu
Dr. Marco Bocchetti
Dr. Michela Falco
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Cancers is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2900 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • multi-omics
  • machine learning
  • sequencing
  • signal transduction
  • molecular mechanisms
  • circulating biomarker
  • cancer

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Published Papers

This special issue is now open for submission.
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